878101P
Avanti
C17 Lyso PAF
Avanti Polar Lipids 878101P, powder
Synonym(s):
1-O-heptadecyl-2-hydroxy-sn-glycero-3-phosphocholine
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About This Item
Empirical Formula (Hill Notation):
C25H54NO6P
CAS Number:
Molecular Weight:
495.67
UNSPSC Code:
12352211
NACRES:
NA.25
Recommended Products
form
powder
packaging
pkg of 1 × 10 mg (878101P-10mg)
manufacturer/tradename
Avanti Polar Lipids 878101P
lipid type
bioactive lipids
phosphoglycerides
shipped in
dry ice
storage temp.
−20°C
SMILES string
O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COCCCCCCCCCCCCCCCCC
General description
C17 Lyso PAF, also known as 1-O-heptadecyl-2-hydroxy-sn-glycero-3-phosphocholine, is a precursor and metabolite of 1-O-heptadecyl-2-acetyl-sn-glycero-3-phosphocholine (C17:0 PAF). Lyso-platelet activating factor (PAF) is synthesized from PAF acetylhydrolases by the degradation of PAF. It is also synthesized from 1-O-alkyl-2-arachidonoyl-sn-glycero-3-phosphocholine (1-alkyl-phosphatidylcholine; PC) by the enzyme phospholipase A2 via the remodeling pathway.
Packaging
5 mL Amber Glass Screw Cap Vial (878101P-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Certificates of Analysis (COA)
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Hideo Shindou et al.
The Journal of biological chemistry, 282(9), 6532-6539 (2006-12-22)
Platelet-activating factor (PAF) is a potent proinflammatory lipid mediator eliciting a variety of cellular functions. Lipid mediators, including PAF are produced from membrane phospholipids by enzymatic cascades. Although a G protein-coupled PAF receptor and degradation enzymes have been cloned and
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