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870520C

Avanti

18:1 CDP DG

Avanti Polar Lipids 870520C

Synonym(s):

1,2-dioleoyl-sn-glycero-3-(cytidine diphosphate) (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C48H91N5O15P2
CAS Number:
799812-77-4
Molecular Weight:
1040.21
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 1 mL (870520C-5mg)
pkg of 1 × 2.5 mL (870520C-25mg)

manufacturer/tradename

Avanti Polar Lipids 870520C

concentration

10 mg/mL (870520C-25mg)
5 mg/mL (870520C-5mg)

lipid type

phosphoglycerides
bioactive lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP(OP(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)C=C2)=O)O1)([O-])=O)([O-])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+]

InChI

1S/C48H85N3O15P2.2H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-43(52)61-37-40(64-44(53)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)38-62-67(57,58)66-68(59,60)63-39-41-45(54)46(55)47(65-41)51-36-35-42(49)50-48(51)56;;/h17-20,35-36,40-41,45-47,54-55H,3-16,21-34,37-39H2,1-2H3,(H,57,58)(H,59,60)(H2,49,50,56);2*1H3/b19-17-,20-18-;;/t40-,41-,45+,46?,47-;;/m1../s1

InChI key

NECNTGAHQCHVGS-BQGZBBTBSA-N

Application

18:1 CDP DG is suitable for liposomes preparation.

Biochem/physiol Actions

18:1 CDP DG or 1,2-dioleoyl-sn-glycero-3-(cytidine diphosphate) produces cytidine 5′?monophosphate by the reaction catalyzed by phosphatidylserine synthase (Pss). CDP-diacylglycerol is derived from diacylglycerol. It serves as a precursor in the production of phosphatidylinositides. Unregulated CDP-diacylglycerol signaling may be associated with the depression.

Packaging

5 mL Clear Glass Sealed Ampule (870520C-25mg)
5 mL Clear Glass Sealed Ampule (870520C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Kimberly R Tyeryar et al.
BMC neuroscience, 9, 12-12 (2008-01-26)
Major depression is a serious mood disorder affecting millions of adults and children worldwide. While the etiopathology of depression remains obscure, antidepressant medications increase synaptic levels of monoamine neurotransmitters in brain regions associated with the disease. Monoamine transmitters activate multiple

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