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856705P

Avanti

16:0 Lyso PE

Avanti Research™ - A Croda Brand, powder

Synonym(s):

1-hexadecanoyl-sn-glycero-3-phosphoethanolamine; PE(16:0/0:0); 110698, Lysophosphatidylethanolamine 16:0

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About This Item

Empirical Formula (Hill Notation):
C21H44NO7P
CAS Number:
53862-35-4
Molecular Weight:
453.55
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (LPE; may contain up to 10% of the 2-LPE isomer, TLC)

form

powder

packaging

pkg of 1 × 200 mg (856705P-200mg)
pkg of 1 × 25 mg (856705P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OCC[NH3+])=O)([H])COC(CCCCCCCCCCCCCCC)=O

Application

16:0 Lyso PE has been used to degranulate human eosinophils. It has also been used to enhance nerve growth factor (NGF)-induced mitogen-activated protein kinase (MAPK) phosphorylation.

Packaging

5 mL Amber Glass Screw Cap Vial (856705P-200mg)
5 mL Amber Glass Screw Cap Vial (856705P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lysophosphatidylcholine enhances NGF-induced MAPK and Akt signals through the extracellular domain of TrkA in PC12 cells
Itakura A, et al.
FEBS Open Bio, 3(1), 243-251 (2013)
Miki Eto et al.
International journal of molecular sciences, 13(12), 16267-16280 (2012-12-05)
Cellular membranes contain glycerophospholipids, which have important structural and functional roles in cells. Glycerophospholipids are first formed in the de novo pathway (Kennedy pathway) and are matured in the remodeling pathway (Lands' cycle). Recently, lysophospholipid acyltransferases functioning in Lands' cycle
Qingxin Shi et al.
Food & function, 10(12), 7782-7792 (2019-11-30)
Triterpenoid saponins from Kuding tea have demonstrated preventive effects on hyperlipidaemia induced by a high-fat diet. Lysoglycerophospholipids (Lyso-GPLs) are known to be associated with proatherogenic conditions such as hyperlipidaemia. In this study, a target profiling strategy based on a multiple
Wuhanqimuge et al.
FEBS open bio, 3, 243-251 (2013-06-19)
Lysophosphatidylcholine (LPC) is one of the major lysophospholipids mainly generated by phospholipase A2 (PLA2)-mediated hydrolysis of phosphatidylcholine (PC). We previously found that LPC displays neurotrophin-like activity in the rat pheochromocytoma PC12 cells and in cerebellar granule neurons, but the molecular
Kimberly D Dyer et al.
Journal of immunology (Baltimore, Md. : 1950), 184(11), 6327-6334 (2010-04-28)
Platelet-activating factor (PAF [1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine]) is a phospholipid mediator released from activated macrophages, mast cells, and basophils that promotes pathophysiologic inflammation. Eosinophil responses to PAF are complex and incompletely elucidated. We show in this article that PAF and its 2-deacetylated metabolite
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