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Key Documents

850745P

Avanti

14:0 PE

Avanti Research - A Croda Brand

Synonym(s):

1,2-ditetradecanoyl-sn-glycero-3-phosphoethanolamine; DMPE; PE(14:0/14:0); 110632

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About This Item

Empirical Formula (Hill Notation):
C33H66NO8P
CAS Number:
Molecular Weight:
635.85
UNSPSC Code:
51191904
NACRES:
NA.25

description

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (850745P-1g)
pkg of 1 × 200 mg (850745P-200mg)
pkg of 1 × 25 mg (850745P-25mg)
pkg of 1 × 500 mg (850745P-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O

InChI

1S/C33H66NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-32(35)39-29-31(30-41-43(37,38)40-28-27-34)42-33(36)26-24-22-20-18-16-14-12-10-8-6-4-2/h31H,3-30,34H2,1-2H3,(H,37,38)/t31-/m1/s1

InChI key

NEZDNQCXEZDCBI-WJOKGBTCSA-N

General description

Phosphatidylethanolamine (PE) is an abundant phospholipid, found in the cells of mammals.

Application

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE):
  • has been used as a phospholipid (PL) internal standard in hydrophilic interaction liquid chromatography tandem mass spectrometry (HILIC-LC-MS/MS)
  • has been used as an internal lipid standard to correct the reproducibility in matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry (MALDI FT-ICR MS) analysis
  • may be used in proteoliposomes for planar supported lipid bilayer formation
  • may be used as a biotinylated internal standard to measure externalization of aminophospholipids (APLs) using mass spectrometry (MS)

Biochem/physiol Actions

Phosphatidylethanolamine (PE) plays a key role in the activity of respiratory complexes. PE also participates in the initiation of autophagy.

Packaging

20 mL Clear Glass Screw Cap Vial (850745P-1g)
20 mL Clear Glass Screw Cap Vial (850745P-500mg)
5 mL Amber Glass Screw Cap Vial (850745P-200mg)
5 mL Amber Glass Screw Cap Vial (850745P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Christopher P Thomas et al.
Nature protocols, 9(1), 51-63 (2013-12-18)
This protocol measures externalization of aminophospholipids (APLs) to the outside of the plasma membrane using mass spectrometry (MS). APL externalization occurs in numerous events, and it is relevant for transplant medicine, immunity and cancer. In this protocol, externalized APLs are
Ana M Campos et al.
Food research international (Ottawa, Ont.), 89(Pt 1), 177-185 (2017-05-04)
Eggs are one of the main foods eaten worldwide. Nutritionally they are one of the main sources of dietary lipids, impacting human health. Egg yolk lipid composition changes depending on different conditions associated with hens raising. Therefore, the purpose of
Alex J B Kreutzberger et al.
Biophysical journal, 115(9), 1755-1761 (2018-10-22)
Intramembrane proteases hydrolyze peptide bonds within the membrane as a regulatory paradigm that is conserved across all forms of cellular life. Many of these enzymes are thought to be oligomeric, and that their resulting quaternary interactions form the basis of
Erum Malik et al.
Biochimica et biophysica acta. Biomembranes, 1862(2), 183141-183141 (2019-12-04)
Linearized esculentin 2 EM (E2EM-lin) from the frog, Glandirana emeljanovi was highly active against Gram-positive bacteria (minimum lethal concentration ≤ 5.0 μM) and strongly α-helical in the presence of lipid mimics of their membranes (>55.0%). The N-terminal α-helical structure adopted by E2EM-lin showed
Paulina Perczyk et al.
Biochimica et biophysica acta. Biomembranes, 1862(2), 183136-183136 (2019-11-22)
Soil fungi play an important role in the environment decomposing dead organic matter and degrading persistent organic pollutants (POP). The presence of hydrophobic POP in the soil and membrane-lytic substances excreted by competing microorganism to the soil solution is the

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