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810282C

Avanti

TopFluor® PE

Avanti Polar Lipids 810282C

Synonym(s):

1-palmitoyl-2-(dipyrrometheneboron difluoride)undecanoyl-sn-glycero-3-phosphoethanolamine

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About This Item

Empirical Formula (Hill Notation):
C45H77BF2N3O8P
CAS Number:
1246355-64-5
Molecular Weight:
867.89
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810282C-1mg)
pkg of 5 × 1 mL (810282C-5mg)

manufacturer/tradename

Avanti Polar Lipids 810282C

concentration

1 mg/mL (810282C-1mg)
1 mg/mL (810282C-5mg)

shipped in

dry ice

storage temp.

−20°C

General description

TopFluor has a moiety, called dipyrromethene boron difluoride. This fluorescent molecule is covalently attached to various lipid molecules. Phosphoethanolamine is a precursor to phosphatidylcholine and phosphatidylethanolamine.

Application

TopFluor® PE may be used as a fluorescently labeled lipid to replace the head labeled lipid (TFPE-head) to study the fusion efficiency of liposomes. It has also been used in the preparation of liposome.

Biochem/physiol Actions

Phosphoethanolamine participates in phospholipid metabolism. It has the ability to repress tumor growth both in vitro and in vivo.

Packaging

5 mL Amber Glass Screw Cap Vial (810282C-1mg)
5 mL Amber Glass Screw Cap Vial (810282C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
Topamax is a registered trademark of Johnson & Johnson

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Single Particle Fluorescence Burst Analysis of Epsin Induced Membrane Fission
Brooks A, et al.
Testing, 10(3) (2015)
Influence of Environmental Conditions on the Fusion of Cationic Liposomes with Living Mammalian Cells
Kolasinac R, et al.
Nanomaterials, 9(7), 1025-1025 (2019)
Fumonisin, Folate, and Neural Tube Defects
Comprehensive Toxicology, 12, 189-208 (2010)
Single Particle Fluorescence Burst Analysis of Epsin Induced Membrane Fission
Brooks A, et al.
PLoS ONE, 10(3) (2015)
Phosphoethanolamine and the danger of unproven drugs
Pondee N, et al.
Ecancermedicalscience (2016)
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