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P1659

Sigma-Aldrich

Pelargonidin chloride

Synonym(s):

3,4′,5,7-Tetrahydroxyflavylium chloride, 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-1-benzopyrylium chloride, Pelargonidol chloride

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About This Item

Empirical Formula (Hill Notation):
C15H11ClO5
CAS Number:
134-04-3
Molecular Weight:
306.70
Beilstein:
3922945
EC Number:
205-127-7
MDL number:
MFCD00017589
UNSPSC Code:
12352100
PubChem Substance ID:
57654503
NACRES:
NA.22

form

powder

storage temp.

2-8°C

SMILES string

[Cl-].Oc1ccc(cc1)-c2[o+]c3cc(O)cc(O)c3cc2O

InChI

1S/C15H10O5.ClH/c16-9-3-1-8(2-4-9)15-13(19)7-11-12(18)5-10(17)6-14(11)20-15;/h1-7H,(H3-,16,17,18,19);1H

InChI key

YPVZJXMTXCOTJN-UHFFFAOYSA-N

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Application

Involved in pharmacological studies investigating the use of flavonoids as inhibitors of CD38

Antioxidant and anthocyanidin:
  • Found in various natural sources evaluated for inhibitory effects on colon and liver cancer cells
  • Used as hyroperoxide and hydrogen peroxide scavenging substance
  • Used to study relationship between structure, antioxidant capacity and redox potentials
  • Studied to determine the mechanism of radical-scavenging

Biochem/physiol Actions

Antioxidant and anthocyanidin.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLCM0906
SLCK5835
SLCH6331
SLCG1721
SLCD5677

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Callistephin chloride ≥95.0% (HPLC)

Sigma-Aldrich

53489

Callistephin chloride

Hamid Sohanaki et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 83, 85-91 (2016-10-25)
Alzheimer's disease (AD) is a multifactorial disorder with devastating outcomes and few mostly palliative available therapeutic strategies. Pelargonidin (Pel), an anthocyanin compound, is an estrogen receptor agonist with lower side effects versus estrogen. This study examined neuroprotective effect of Pel
Catherine Felgines et al.
The Journal of nutrition, 133(5), 1296-1301 (2003-05-06)
Anthocyanins are phenolic compounds widely distributed in fruits and vegetables. Their consumption has been shown to prevent some chronic diseases. Anthocyanin metabolism, however, is still not fully understood. The aim of this work was to evaluate the bioavailability of anthocyanins
Chan Ho Jang et al.
Nutrients, 11(4) (2019-04-17)
Certain antioxidative flavonoids are known to activate nuclear factor E2-related factor 2 (Nrf2), a transcription factor that regulates cellular antioxidants and detoxifying response and is reportedly highly activated in many types of cancers. Few studies on the potential undesired effects
Sridaran Dhivya et al.
Integrative cancer therapies, 15(4), 525-534 (2016-05-06)
Hypothesis Anthocyanins possess well-known biological effects and suppress DNA damage induced by therapeutic topoisomerase poisons. Our study focusses on the modulatory effects of anthocyanidins-malvidin (MAL) and pelargonidin (PEL)-on topoisomerase II poison mitoxantrone (MXT)-induced cytotoxicity and genotoxicity in in vitro and
Gabor Kottra et al.
The Journal of pharmacology and experimental therapeutics, 322(2), 829-835 (2007-05-15)
There is controversy as to whether intestinal absorption of glycosylated flavonoids, and particularly quercetin glycosides, involves their uptake in intact form via the human sodium-coupled glucose transporter hSGLT1. We here describe studies using Xenopus oocytes that express hSGLT1 and the
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Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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