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925144

Sigma-Aldrich

KB05yne

≥95%

Synonym(s):

4-(N-(4-Bromophenyl)acrylamido)-N-(hex-5-yn-1-yl)benzamide, Functionalized scout fragment

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About This Item

Empirical Formula (Hill Notation):
C22H21BrN2O2
Molecular Weight:
425.32
UNSPSC Code:
12352101
NACRES:
NA.22

Quality Level

Assay

≥95%

form

powder or solid

reaction suitability

reagent type: chemical modification reagent
reaction type: click chemistry

storage temp.

2-8°C

Application

KB05yne is a cysteine-reactive small-molecule fragment for chemoproteomic and ligandability studies for both traditionally druggable proteins as well as "undruggable," or difficult-to-target, proteins. This fragment electrophile is the functionalized version of KB02 (912131)

Related useful products may include: Cysteine-reactive fragments: KB02 (912131), KB03 (912654), KB05 (911798), sulfoxide (925136), CoLDR probe (923818) Functionalized scout fragments: KB02-COOH (925047), KB02yne (925225) Electrophilic degraders featuring scout fragments: KB02-SLF (914738), KB03-SLF (914975), KB05-SLF (913715), Biotin-SLF (914223) Cysteine-reactive probes for chemoproteomics: IA alkyne (924237), IA 5-TAMRA (925020), desthiobiotin iodoacetamide (923826), or biotin iodoacetamide (B2059)Related useful products may include: Cysteine-reactive fragments: KB02 (912131), KB03 (912654), KB05 (911798), sulfoxide (925136), CoLDR probe (923818) Functionalized scout fragments: KB02-COOH (925047), KB02yne (925225) Electrophilic degraders featuring scout fragments: KB02-SLF (914738), KB03-SLF (914975), KB05-SLF (913715), Biotin-SLF (914223) Cysteine-reactive probes for chemoproteomics: IA alkyne (924237), IA 5-TAMRA (925020), desthiobiotin iodoacetamide (923826), or biotin iodoacetamide (B2059)

Technology spotlight: Proteomic Ligandability Assessment

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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