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900173

Sigma-Aldrich

Fluorescent nanodiamond

Nitrogen vacancy >60 NVN/particle, 70 nm avg. part. size (DLS), 1 mg/mL in deionized water

Synonym(s):

Nanodiamond

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About This Item

UNSPSC Code:
12352302
NACRES:
NA.23

description

+56.7 mV ±20%

Quality Level

100

form

dispersion
nanoparticles

composition

Nitrogen vacancy, >60 NVN/particle

concentration

1 mg/mL in deionized water

avg. part. size

70 nm (DLS)

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General description

Green fluorescent nanodiamond.

Application

Nanodiamonds containing N-V-N color centers exhibit green fluorescence. These do not photobleach or photoblink and find applications in fluorescent bioimaging, cathode luminescent imaging, stimulated emission depletion (STED) imaging etc. In combination with NDs emitting in red fluorescence (N-V), it provides opportunities for multicolor imaging.

Storage Class Code

10 - Combustible liquids

WGK

nwg

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Romana Schirhagl et al.
Annual review of physical chemistry, 65, 83-105 (2013-11-28)
Crystal defects in diamond have emerged as unique objects for a variety of applications, both because they are very stable and because they have interesting optical properties. Embedded in nanocrystals, they can serve, for example, as robust single-photon sources or
Nanodiamond bioconjugate probes and their collection by electrophoresis.
Hens SC, et al.
Diamond and Related Materials, 17, 1858-1858 (2008)
Highly Fluorescent Nanodiamonds Protein-Functionalized for Cell Labeling and Targeting.
Chang B, et al.
Advances in Functional Materials, 23, 5737-5737 (2013)
Yuen Yung Hui et al.
Optics express, 18(6), 5896-5905 (2010-04-15)
Dynamics of fluorescent diamond nanoparticles in HeLa cells has been studied with two-photon fluorescence correlation spectroscopy (FCS). Fluorescent nanodiamond (FND) is an excellent fluorescent probe for bioimaging application, but they are often trapped in endosomes after cellular uptake. The entrapment
Functionality is Key: Recent Progress in the Surface Modification of Nanodiamond.
Krueger A and Lang D
Advances in Functional Materials, 22, 890-890 (2012)
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Fluorescent Nanodiamond Particles: Properties and Applications

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Functionalization of Fluorescent Nanodiamonds for Bioimaging

Properties & characteristics of Fluorescent Nanodiamonds & biofunctionalization strategies explained. Conjugation protocols for streptavidin functionalization, biotinylation & coupling biotinylated/streptavidin provided. FNDs may be used for labeling of low-level expressed targets, Bioimaging & Bioconjugation.

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