Skip to Content
Merck
All Photos(1)

Key Documents

714836

Sigma-Aldrich

Iodine monochloride solution

1 M in acetic acid

Synonym(s):

Chloroiodide solution, Wijs solution

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
ICl
CAS Number:
Molecular Weight:
162.36
Beilstein:
3587194
MDL number:
UNSPSC Code:
12352101
PubChem Substance ID:
NACRES:
NA.22

form

solution

Quality Level

concentration

1 M in acetic acid

density

1.143 g/mL at 25 °C

SMILES string

ClI

InChI

1S/ClI/c1-2

InChI key

QZRGKCOWNLSUDK-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Iodine monochloride is an inorganic reagent used in the iodination and chloroiodination of aromatic and unsaturated compounds, respectively. It is also used to cleave carbon-metal bonds.

Application

Iodine monochloride can be used:
  • As a reagent in the preparation of α-iodo β-ketosulfones from β-ketosulfones.
  • In the synthesis of 3-(4-bromo-2-methylphenyl)-4-iodosydnone, which is further used to prepare substituted pyrazoles.

Pictograms

FlameCorrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

105.1 °F

Flash Point(C)

40.6 °C


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synthesis of α-iodo β-ketosulfones and α-iodo methylsulfones using iodine monochloride
Suryakiran N, et al.
Tetrahedron Letters, 47(26), 4319-4323 (2006)
R G Nielsen et al.
Journal of chromatography, 423, 41-50 (1987-12-25)
Low-level adsorption on the stationary phase has been studied using immunochemical reagents. An immunoaffinity column has been evaluated using affinity-purified radioisotope-labeled monoclonal antibodies. Recovery experiments including continuous immunosorbent monitoring have been performed. Proper characterization of an immunoaffinity separation can result
A Gafni
Biochimica et biophysica acta, 742(1), 91-99 (1983-01-12)
Rat muscle glyceraldehyde-3-phosphate dehydrogenase was reacted with two reagents aimed at the highly reactive cysteine-149 residue in the active site of the enzyme. The enzyme was rapidly inactivated by iodine monochloride. Complete inactivation occurred when approx. 6 mol ICl were
Zan Qu et al.
Journal of hazardous materials, 183(1-3), 132-137 (2010-08-03)
The removal of Hg(0) by the homogenous gas-phase reaction and particle-induced reaction was investigated under various conditions. Iodine monochloride was found to be efficient for Hg(0) oxidation, with the apparent 2nd-order rate constant of about 10.5(±0.3)×10(-17) cm(3) molecules(-1) s(-1) and
K R Siebenlist et al.
Biochemistry, 39(46), 14171-14175 (2000-11-23)
There are conflicting ideas regarding the location of the carboxyl-terminal regions of cross-linked gamma-chain dimers in double-stranded fibrin fibrils. Some investigators believe that the chains are always oriented longitudinally along each fibril strand and traverse the contacting ends of abutting

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service