654213

2-Methylpyridine borane complex

95%

• Synonym(s): 2-Picoline borane complex
• CAS Number: 3999-38-0
• MDL number: MFCD11042668
• UNSPSC Code: 12352005
• PubChem Substance ID: 24884021
• NACRES: NA.22

Properties

• Assay: 95%
• form: solid
• reaction suitability: reagent type: reductant
• storage temp.: 2-8°C
• SMILES string: CC1=NC=CC=C1.B
• InChI: 1S/C6H7N.B/c1-6-4-2-3-5-7-6;/h2-5H,1H3;
• InChI key: QHXLIQMGIGEHJP-UHFFFAOYSA-N

Description

General description

2-Methylpyridine borane complex is a nontoxic alternate to the reducing agent sodium cyanoborohydride.

Application

2-Methylpyridine borane complex solution (2-Picoline borane complex) was used as reducing agent for the labeling of oligosaccharides by reductive amination. It may be used in the following studies:

• Synthesis of alkoxyamine derivatives, via reduction of oxime ethers.
• Reductive amination reactions of C₁-C₁₀ aldehyde 2,4-dinitrophenylhydrazones.
• Synthesis of various trifluoromethylated amino compounds.
• An alternative reagent for reductive aminations.

Environmentally benign reducing agent

Reactant for:
Reductive amination
N-Benzyl-protection of amino acid derivatives by reductive alkylation
Reductive alkoxyamination

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H261,H315,H319,H335
• Precautionary Statements: P231 + P232 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 - Water-react 2
• Target Organs: Respiratory system
• Storage Class Code: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• WGK: WGK 3
• Flash Point(F): 212.0 °F - closed cup
• Flash Point(C): 100 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves