345113

Di-n-butylmagnesium solution

1.0 M in heptane

• Synonym(s): Bis-n-butylmagnesium, Dibutylmagnesium
• Linear Formula: [CH₃(CH₂)₃]₂Mg
• CAS Number: 1191-47-5
• Molecular Weight: 138.53
• Beilstein: 3535184
• MDL number: MFCD00015225
• UNSPSC Code: 12352103
• PubChem Substance ID: 24861295
• NACRES: NA.22

Properties

• reaction suitability: reaction type: Grignard Reaction
• concentration: 1.0 M in heptane
• density: 0.713 g/mL at 25 °C
• SMILES string: CCCC[Mg]CCCC
• InChI: 1S/2C4H9.Mg/c2*1-3-4-2;/h2*1,3-4H2,2H3;
• InChI key: ODHFJIDDBSDWNU-UHFFFAOYSA-N

Description

General description

Di-n-butylmagnesium solution is a useful reagent for the synthesis of organomagnesium compounds.

Application

Di-n-butylmagnesium solution can be used as a reagent for the deprotection of aromatic and aliphatic benzyl thioethers to synthesize corresponding benzylthiols in the presence of titanocene dichloride. It can also be used as a catalyst to synthesize enantioenriched nitrogen-containing heterocyclic derivatives by the asymmetric ring-opening reaction of aziridines with substituted tetrazoles in the presence of chiral ligand.

Safety Information

• Pictograms: GHS02,GHS08,GHS05,GHS07,GHS09
• Signal Word: Danger
• Hazard Statements: H225,H250,H260,H304,H314,H336,H410
• Precautionary Statements: P210 - P231 + P232 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P370 + P378
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Pyr. Liq. 1 - Skin Corr. 1B - STOT SE 3 - Water-react 1
• Target Organs: Central nervous system
• Supplementary Hazards: EUH014
• Storage Class Code: 4.2 - Pyrophoric and self-heating hazardous materials
• WGK: WGK 2
• Flash Point(F): 21.2 °F - closed cup
• Flash Point(C): -6 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves