Skip to Content
Merck
All Photos(1)

Key Documents

More Documents

227714

Sigma-Aldrich

3,4,5-Trimethoxytoluene

97%

Synonym(s):

5-Methylpyrogallol trimethyl ether

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
(CH3O)3C6H2CH3
CAS Number:
6443-69-2
Molecular Weight:
182.22
Beilstein:
1953791
EC Number:
229-239-0
MDL number:
MFCD00008397
UNSPSC Code:
12352100
PubChem Substance ID:
24853648
NACRES:
NA.22

Assay

97%

refractive index

n20/D 1.523 (lit.)

bp

117-118 °C/5 mmHg (lit.)

mp

24-26 °C (lit.)

density

1.082 g/mL at 25 °C (lit.)

SMILES string

COc1cc(C)cc(OC)c1OC

InChI

1S/C10H14O3/c1-7-5-8(11-2)10(13-4)9(6-7)12-3/h5-6H,1-4H3

InChI key

KCIZTNZGSBSSRM-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

3,4,5-Trimethoxytoluene was used as a substructure model compound in the reaction of trimethoprim with free available chlorine (i.e. HOCl).

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

165.2 °F - closed cup

Flash Point(C)

74 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

(±)-α-Tocopherol synthetic, ≥96% (HPLC)

Sigma-Aldrich

T3251

(±)-α-Tocopherol

Ah-Reum Han et al.
Chemistry & biodiversity, 5(2), 346-351 (2008-02-23)
Bioassay-guided fractionation of the root extract of Asarum sieboldii led to the isolation of the four active compounds (-)-sesamin (1), (2E,4E,8Z,10E)-N-(2-methylpropyl)dodeca-2,4,8,10-tetraenamide (2), kakuol (3), and '3,4,5-trimethoxytoluene' (=1,2,3-trimethoxy-5-methylbenzene; 4), in terms of inhibition of lipopolysaccharide (LPS)-induced nitric oxide (NO) production. Compounds
Chia-Lin Lee et al.
PloS one, 7(5), e37897-e37897 (2012-06-06)
In a structure-activity relationship (SAR) study, 3-methoxy-1,4-phenanthrenequinones, calanquinone A (6a), denbinobin (6b), 5-OAc-calanquinone A (7a) and 5-OAc-denbinobin (7b), have significantly promising cytotoxicity against various human cancer cell lines (IC(50) 0.08-1.66 µg/mL). Moreover, we also established a superior pharmacophore model for
Michael C Dodd et al.
Water research, 41(3), 647-655 (2006-12-19)
Trimethoprim (TMP), one of the antibacterials most frequently detected in municipal wastewaters and surface waters, reacts readily with free available chlorine (i.e., HOCl) at pH values between 3 and 9 (e.g., the pH-dependent apparent second-order rate constant, k''(app)=5.6 x 10(1)M(-1)s(-1)
Olga V Zalomaeva et al.
Dalton transactions (Cambridge, England : 2003), 46(16), 5202-5209 (2017-04-01)
The selective oxidation of methoxy/methyl-substituted arenes to the corresponding benzoquinones has been first realized using aqueous hydrogen peroxide as a green oxidant, acid tetrabutylammonium salts of the γ-Keggin divanadium-substituted phosphotungstate [γ-PW

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service