210218

3-(Dimethylamino)-1,2-propanediol

98%

• Synonym(s): (±)-3-(Dimethylamino)-1,2-propanediol, 1,2-Dihydroxy-3-(dimethylamino)propane, Methicol
• Linear Formula: (CH₃)₂NCH₂CH(OH)CH₂OH
• CAS Number: 623-57-4
• Molecular Weight: 119.16
• EC Number: 210-802-4
• MDL number: MFCD00004714
• UNSPSC Code: 12352100
• PubChem Substance ID: 24852622
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 98%
• refractive index: n20/D 1.4609 (lit.)
• bp: 216-217 °C (lit.)
• density: 1.004 g/mL at 25 °C (lit.)
• functional group: amine; hydroxyl
• SMILES string: CN(C)CC(O)CO
• InChI: 1S/C5H13NO2/c1-6(2)3-5(8)4-7/h5,7-8H,3-4H2,1-2H3
• InChI key: QCMHUGYTOGXZIW-UHFFFAOYSA-N

Description

Application

3-(Dimethylamino)-1,2-propanediol was used in the preparation of:

• synthetic cationic lipid, N-[1-(2,3-dioleyloxy)propyl-N,N,N-trimethylammonium chloride (DOTMA), used in DNA-transfection protocol
• indane-derived bis(oxazolines)

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): 221.0 °F - closed cup
• Flash Point(C): 105 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves