Skip to Content
Merck
All Photos(1)

Key Documents

More Documents

170518

Sigma-Aldrich

1-Naphthyl isocyanate

98%

Synonym(s):

α-Naphthyl isocyanate, 1-Isocyanatonaphthalene, 1-Naphthalene isocyanate, Naphthalen-1-ylisocyanate

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
C10H7NCO
CAS Number:
86-84-0
Molecular Weight:
169.18
Beilstein:
742779
EC Number:
201-703-7
MDL number:
MFCD00003881
UNSPSC Code:
12352100
PubChem Substance ID:
24850308
NACRES:
NA.22

Quality Level

100

Assay

98%

form

liquid

refractive index

n20/D 1.6344 (lit.)

bp

267 °C/761 mmHg (lit.)

mp

4 °C (lit.)

solubility

alcohol: soluble
chloroform: soluble
diethyl ether: soluble

density

1.177 g/mL at 25 °C (lit.)

SMILES string

O=C=Nc1cccc2ccccc12

InChI

1S/C11H7NO/c13-8-12-11-7-3-5-9-4-1-2-6-10(9)11/h1-7H

InChI key

BDQNKCYCTYYMAA-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

1-Naphthyl isocyanate was used in the preparation of cationic aromatic urethane.

Pictograms

Exclamation markHealth hazard
GHS07,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Christopher J McEntyre et al.
Analytica chimica acta, 644(1-2), 90-94 (2009-05-26)
Choline is an essential nutrient which is difficult to measure because it has no native absorbance or fluorescence and only relatively unreactive functional groups. The method described here uses the reaction of the hydroxyl group on choline with 1-naphthyl isocyanate
Q Yang et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 24(4), 285-289 (1989-01-01)
alpha-Naphthyl isocyanate (NI) as a derivatizing agent to separate several beta-blockers was described. This procedure is simple, rapid and gives good resolution. Experiments with NI derivatives of alprenolol showed that the isocyanate group reacted with the amino group on the
Desheng Zhai et al.
Planta medica, 73(2), 128-133 (2007-01-09)
Alpha-naphthyl isothiocyanate (ANIT) is a known hepatotoxicant that causes acute cholestatic hepatitis characterized by the infiltration of neutrophils around bile ducts and necrotic hepatocytes. The effects of glycyrrhizin (GL), 18beta-glycyrrhetinic acid (GA), matrine (MT), oxymatrine (OMT), salvianolic acid B (SAB)
Ying Zhao et al.
Toxicology, 230(2-3), 145-150 (2006-12-23)
A pharmacokinetic study was carried out in rats to investigate the effects of experimental hepatic injury on the liver glucuronidation and bile excretion of ketoprofen (KP) and its glucuronides (KPGs). In vivo, KP (20mg/kg b.w.) was intravenously administered to carbon
Shashi K Ramaiah et al.
Toxicologic pathology, 35(6), 757-766 (2007-10-19)
Polymorphonuclear leukocytes (neutrophils) are essential in the defense against invading microorganisms, tissue trauma or any inciting inflammatory signals. Hepatic infiltration of neutrophils is an acute response to recent or ongoing liver injury, hepatic stress or unknown systemic inflammatory signals. Once
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service