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Merck

1643452

USP

特拉唑嗪 盐酸盐 二水合物

United States Pharmacopeia (USP) Reference Standard

别名:

Terazosin hydrochloride dihydrate, 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]piperazine hydrochloride dihydrate

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About This Item

经验公式(希尔记法):
C19H25N5O4 · HCl · 2H2O
CAS号:
分子量:
459.92
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

terazosin

製造商/商標名

USP

應用

pharmaceutical (small molecule)

格式

neat

SMILES 字串

O.O.Cl.COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)C4CCCO4

InChI

1S/C19H25N5O4.ClH.2H2O/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;;;/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22);1H;2*1H2

InChI 密鑰

NZMOFYDMGFQZLS-UHFFFAOYSA-N

基因資訊

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一般說明

Terazosin hydrochloride is a quinazoline derivative. It is a alpha-1-selective adrenoceptor blocking agent. It has been used to treat hypertension, as it helps the blood vessels to relax, expand and improves blood flow.

應用

Terazosin hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Terazosin Capsules
  • Terazosin Tablets

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Terazosin potentiometric sensor for quantitative analysis of terazosin hydrochloride in pharmaceutical formulation based on computational study.
Hosseini, Morteza, Ensieh Nasli-Esfahani, and Parviz Norouzi.
International Journal of Electrochemical Science, 5, 200-214 (2010)
Potentiometric and fluorimetric methods for the determination of terazosin HCl in drug substance and dosage forms.
Ismail, Nahla S., and Taghreed A. Mohamed.
International Journal of Electrochemical Science, 9, 7394-7394 (2014)
Peter B Schwarz et al.
The Journal of physiology, 592(16), 3597-3609 (2014-05-27)
Noradrenergic neurotransmission in the brainstem is closely coupled to changes in muscle activity across the sleep-wake cycle, and noradrenaline is considered to be a key excitatory neuromodulator that reinforces the arousal-related stimulus on motoneurons to drive movement. However, it is

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