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Merck

1602502

USP

视黄醇(维生素A)棕榈酸酯 CRM

United States Pharmacopeia (USP) Reference Standard

别名:

全−反式−视黄醇棕榈酸酯, 维生素 A 棕榈酸酯

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About This Item

经验公式(希尔记法):
C36H60O2
CAS号:
分子量:
524.86
Beilstein:
1917366
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

retinyl compounds

製造商/商標名

USP

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(CCCCCCCCCCCCCCC)=O)C(C)(C)CCC1

InChI

1S/C36H60O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-25-35(37)38-30-28-32(3)23-20-22-31(2)26-27-34-33(4)24-21-29-36(34,5)6/h20,22-23,26-28H,7-19,21,24-25,29-30H2,1-6H3/b23-20+,27-26+,31-22+,32-28+

InChI 密鑰

VYGQUTWHTHXGQB-FFHKNEKCSA-N

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一般說明

本品按现行药典规定交付。所有为支持本产品而提供的信息,包括 SDS 和任何产品信息小册子,均由药典颁发机构制定和发布。
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應用


  • Retinyl palmitate in nanoemulgels for skin diseases: Research explores the application of retinyl palmitate in innovative nanoemulgels, demonstrating its efficacy in treating skin conditions through enhanced delivery mechanisms. This aligns with its use in skin rejuvenation and anti-aging treatments, providing a novel approach for topical therapy (Sghier et al., 2024).

  • Stability and efficacy in UVB-induced skin photoaging: A study assessed retinyl palmitate′s efficacy against UVB-induced photoaging, showing significant protective effects on the skin. This underscores its potential as a high-purity biochemical assay component for studying retinoid signaling and its impact on skin health (Shu et al., 2023).

  • Enhanced anti-photoaging therapy: Comparative research among various retinoids, including retinyl palmitate, highlights its superior anti-inflammatory and antioxidative activities, positioning it as a preferred choice for anti-photoaging treatments. The study emphasizes its application in biochemical assays and as a vitamin A source in tissue engineering (Shu et al., 2023).

生化/生理作用

评论:维生素 A 代谢。

分析報告

这些产品仅供测试和分析使用。它们不适用于人类或动物的给药,不可用于诊断、治疗或治愈任何疾病。

其他說明

可能适用相应的销售限制。

象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Aquatic Chronic 3 - Repr. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 2

閃點(°F)

381.2 °F

閃點(°C)

194.00 °C


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

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访问文档库

Vitamin A
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 44(2), 4632-4632 (2019)
Shaikh Meshbahuddin Ahmad et al.
Contemporary clinical trials, 39(2), 269-279 (2014-10-02)
In recent years, neonatal vitamin A supplementation is considered as an essential infant-survival intervention but the evidence is not conclusive. This randomized controlled clinical trial was conducted to evaluate the effect of vitamin A on immune competence in early infancy.
Hans L Mooij et al.
Journal of lipid research, 56(3), 665-673 (2015-01-09)
Elevated nonfasting TG-rich lipoprotein levels are a risk factor for CVD. To further evaluate the relevance of LDL-receptor (LDLr) pathway and heparan sulfate proteoglycans (HSPGs) in TG homeostasis, we analyzed fasting and postprandial TG levels in mice bearing combined heterozygous
Xiaofeng Liao et al.
PloS one, 10(3), e0118176-e0118176 (2015-03-17)
Roles of all-trans-retinoic acid (tRA), a metabolite of vitamin A (VA), in both tolerogenic and immunogenic responses are documented. However, how tRA affects the development of systemic autoimmunity is poorly understood. Here we demonstrate that tRA have paradoxical effects on
Zheng-wang Sun et al.
Journal of natural medicines, 69(1), 22-34 (2014-09-18)
Galla chinensis (GAC) is a natural traditional Chinese medicine that has been widely used in folk medicine. Although GAC compounds (mainly gallic acid and methyl gallate) possess strong antiviral, antibacterial, anticancer, and antioxidant activities, there is no report regarding topical

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