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等級
pharmaceutical primary standard
API 家族
penicillin & derivatives
製造商/商標名
USP
應用
pharmaceutical (small molecule)
格式
neat
SMILES 字串
[K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O
InChI
1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1
InChI 密鑰
IYNDLOXRXUOGIU-LQDWTQKMSA-M
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一般說明
Penicillin G is a β-lactam antibiotic having antimicrobial action against Gram-positive and Gram-negative bacteria. Penicillin G potassium USP reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
應用
Penicillin G potassium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Penicillamine
- Penicillin G Benzathine
- Penicillin G Benzathine and Penicillin G Procaine Injectable Suspension
- Penicillin G Benzathine Injectable Suspension
- Penicillin G Potassium
- Penicillin G Potassium for Injection
- Penicillin G Potassium for Oral Solution
生化/生理作用
作用机制:青霉素G通过与青霉素结合蛋白(PBP)结合抑制肽聚糖链交联,从而抑制细胞壁合成。
抗菌谱:本品具有抗革兰氏阳性菌和革兰氏阴性菌活性。
抗菌谱:本品具有抗革兰氏阳性菌和革兰氏阴性菌活性。
其他說明
This product is part of the USP Biologics program.
Sales restrictions may apply.
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其他客户在看
Journal of AOAC International, 97(4), 1225-1229 (2014-08-26)
A cloud point extraction (CPE) method for determination of trace amounts of penicillin G by spectrophotometry based on its effect on the triiodide ion (I3(-)) has been developed. Penicillin G is converted to the corresponding penicilloic acid by carrying out
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 113(1), 75-81 (2014-05-27)
The absence of commercially available penicilloyl-polylysine (PPL) for most of the last decade severely hampered the practice of penicillin allergy evaluation because skin testing without PPL is reported to have a poor negative predictive value (NPV). To determine the safety
Chronic inflammatory demyelinating polyneuropathy associated with neurosyphilis.
The American journal of the medical sciences, 349(1), 90-91 (2014-12-04)
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