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Merck

1502508

USP

青霉素G钾

United States Pharmacopeia (USP) Reference Standard

别名:

青霉素G 钾盐, 苄青霉素 钾盐

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About This Item

经验公式(希尔记法):
C16H17KN2O4S
CAS号:
分子量:
372.48
Beilstein:
3832841
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

penicillin & derivatives

製造商/商標名

USP

應用

pharmaceutical (small molecule)

格式

neat

SMILES 字串

[K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O

InChI

1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

InChI 密鑰

IYNDLOXRXUOGIU-LQDWTQKMSA-M

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一般說明

Penicillin G is a β-lactam antibiotic having antimicrobial action against Gram-positive and Gram-negative bacteria. Penicillin G potassium USP reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Penicillin G potassium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Penicillamine
  • Penicillin G Benzathine
  • Penicillin G Benzathine and Penicillin G Procaine Injectable Suspension
  • Penicillin G Benzathine Injectable Suspension
  • Penicillin G Potassium
  • Penicillin G Potassium for Injection
  • Penicillin G Potassium for Oral Solution

生化/生理作用

作用机制:青霉素G通过与青霉素结合蛋白(PBP)结合抑制肽聚糖链交联,从而抑制细胞壁合成。

抗菌谱:本品具有抗革兰氏阳性菌和革兰氏阴性菌活性。

其他說明

This product is part of the USP Biologics program.
Sales restrictions may apply.

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说明
价格

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

防範說明

危險分類

Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

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Nahid Pourreza et al.
Journal of AOAC International, 97(4), 1225-1229 (2014-08-26)
A cloud point extraction (CPE) method for determination of trace amounts of penicillin G by spectrophotometry based on its effect on the triiodide ion (I3(-)) has been developed. Penicillin G is converted to the corresponding penicilloic acid by carrying out
Matthieu Picard et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 113(1), 75-81 (2014-05-27)
The absence of commercially available penicilloyl-polylysine (PPL) for most of the last decade severely hampered the practice of penicillin allergy evaluation because skin testing without PPL is reported to have a poor negative predictive value (NPV). To determine the safety
Chronic inflammatory demyelinating polyneuropathy associated with neurosyphilis.
Evangelia Kararizou et al.
The American journal of the medical sciences, 349(1), 90-91 (2014-12-04)

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