1463326

Anatabine

United States Pharmacopeia (USP) Reference Standard

• 别名: Anatabine, (RS)-Anatabine, (±)-Anatabine, 1,2,3,6-Tetrahydro-2,3′-bipyridine, 1,2,3,6-Tetrahydro-2,3′-dipyridine
• 经验公式（希尔记法）: C₁₀H₁₂N₂
• CAS号: 2743-90-0
• 分子量: 160.22
• MDL號碼: MFCD00078278
• 分類程式碼代碼: 41116107
• NACRES: NA.24

属性

• 等級: pharmaceutical primary standard
• API 家族: nicotine
• 製造商／商標名: USP
• 應用: pharmaceutical (small molecule)
• 形式: neat
• 儲存溫度: 2-8°C
• SMILES 字串: N1C(CC=CC1)c2cnccc2
• InChI: 1S/C10H12N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h1-4,6,8,10,12H,5,7H2
• InChI 密鑰: SOPPBXUYQGUQHE-UHFFFAOYSA-N

说明

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Nicotine Related Compound A USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as:

• Nicotine
• Nicotine Polacrilex

生化／生理作用

Anatabine is a blood-brain barrier penetrant minor alkaloid, a cholinergic agonist, isolated from Solanaceae plant family that exhibits anti-inflammatory properties.

Anatabine is a blood-brain barrier penetrant minor alkaloid, a cholinergic agonist, isolated from Solanaceae plant family that exhibits anti-inflammatory properties. Apparently, anti-inflammatory properties of anatabine are partially mediated by inhibition of STAT3 and p65 NFkB phosphorylation. Anatabine decreases the transcription and protein synthesis of β-secretase (BACE-1), and appears to ameliorate experimental autoimmune thyroiditis and encephalomyelitis.

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301,H319
• 防範說明: P264 - P270 - P280 - P301 + P310 - P305 + P351 + P338 - P337 + P313
• 危險分類: Acute Tox. 3 Oral - Eye Irrit. 2
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable