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Merck
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主要文件

1411038

USP

Methimazole Related Compound C

United States Pharmacopeia (USP) Reference Standard

别名:

1-Methyl-2-(methylthio)-1H-imidazole, 1-Methyl-2-(methylsulphanyl)-1H-imidazole

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About This Item

经验公式(希尔记法):
C5H8N2S
CAS号:
分子量:
128.20
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

methimazole

製造商/商標名

USP

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

2-8°C

InChI

1S/C5H8N2S/c1-7-4-3-6-5(7)8-2/h3-4H,1-2H3

InChI 密鑰

LKIVEIAXFZBGMO-UHFFFAOYSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

應用


  • Nephrotoxicity Studies in Renal Cells: Methimazole Related Compound C was used in a study to explore the role of biotransformation and oxidative stress in 3,5-dichloroaniline-induced nephrotoxicity. This research provides insights into the cellular mechanisms affected by Methimazole and its related compounds(Racine et al., 2016).


  • Phenytoin Teratogenicity Research: Investigations into the bioactivation of phenytoin, involving lipoxygenase-catalyzed reactions that may be relevant to Methimazole Related Compound C, provide critical data on the enzymatic pathways that contribute to drug-induced teratogenic effects. This research assists in the development of safer pharmaceuticals by identifying hazardous metabolites (Yu and Wells, 1995).


  • Enzyme Inhibition Studies: The impact of thionamides and related compounds on enzyme activities was studied, highlighting how Methimazole Related Compound C affects important metabolic enzymes like trimethylamine oxidase. This is essential for developing medications that minimize adverse effects on metabolic processes (Pearson et al., 1982).


分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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