1335610

Ibutilide fumarate

United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 885.23 ([(C₂₀H₃₆N₂O₃S)₂ . C₄H₄O₄])

• 别名: Ibutilide hemifumarate salt, (±)-N-[4-[4-(Ethylheptylamino)-1-hydroxybutyl]phenyl]-methanesulfonamide hemifumarate salt, Corvert
• 经验公式（希尔记法）: C₂₀H₃₆N₂O₃S · 0.5C₄H₄O₄
• CAS号: 122647-32-9
• 分子量: 442.61
• MDL號碼: MFCD01715410
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329750146
• NACRES: NA.24

属性

• 等級: pharmaceutical primary standard
• API 家族: ibutilide
• 分子量: monograph mol wt. 885.23
• 製造商／商標名: USP
• 應用: pharmaceutical (small molecule)
• 格式: neat
• 儲存溫度: 2-8°C
• SMILES 字串: OC(=O)\C=C\C(O)=O.CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1.CCCCCCCN(CC)CCCC(O)c2ccc(NS(C)(=O)=O)cc2
• InChI: 1S/2C20H36N2O3S.C4H4O4/c2*1-4-6-7-8-9-16-22(5-2)17-10-11-20(23)18-12-14-19(15-13-18)21-26(3,24)25;5-3(6)1-2-4(7)8/h2*12-15,20-21,23H,4-11,16-17H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+
• InChI 密鑰: PCIOHQNIRPWFMV-WXXKFALUSA-N
• 基因資訊: human ... KCNH2(3757)

说明

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Ibutilide fumarate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

生化／生理作用

Ibutilide hemifumarate salt is considered a new generation "pure" Class III antiarrhythmic agent. Ibutilide binds to and alters the activity of hERG potassium channels, delayed inward rectifier potassium (IKr) channels and L-type (dihydropyridine sensitive) calcium channels.

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

安全信息

• 象形圖: GHS08,GHS07
• 訊號詞: Warning
• 危險聲明: H302,H361d
• 防範說明: P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
• 危險分類: Acute Tox. 4 Oral - Repr. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable