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Merck

59352-U21

Supelco

Discovery® C8 (5 µm) HPLC Columns

L × I.D. 5 cm × 2.1 mm, HPLC Column

别名:

C8 Reversed-Phase Chromatography Column

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About This Item

分類程式碼代碼:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Discovery ® C8 HPLC 色谱柱, 5 μm particle size, L × I.D. 5 cm × 2.1 mm

材料

stainless steel column

agency

suitable for USP L7

產品線

Discovery®

特點

endcapped

製造商/商標名

Discovery®

包裝

1 ea of

標籤範圍

7.5% Carbon loading

參數

≤70 °C temp. range
400 bar pressure (5801 psi)

技術

HPLC: suitable
LC/MS: suitable

長度 × 內徑

5 cm × 2.1 mm

表面積

200 m2/g

表面覆盖率

3.4 μmol/m2

雜質

<10 ppm metals

基質

silica gel, high purity, spherical base material
fully porous particle

基質活性組

C8 (octyl) phase

粒徑

5 μm

孔徑

180 Å

工作pH值範圍

2-8

應用

food and beverages

分離技術

reversed phase

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應用


  • UHPLC-MS/MS method for chiral separation of 3-hydroxy fatty acids: Highlighting the adaptability of the Discovery® C8 column, this paper details its application in a sophisticated chiral separation method, underscoring its importance in clinical diagnostics and research (Fu et al., 2023).

特點和優勢

  • 优良的重现性。
  • 分析强疏水性化合物时比 C18 柱快
  • 稳定性好、低流失,适用于 LC-MS 分析
  • 分析碱性和酸性化合物均可获得良好峰形
  • 可兼容低有机溶剂/高含水量的流动相

法律資訊

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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Scott C Bell et al.
Pharmacology & therapeutics, 145, 19-34 (2014-06-17)
With the discovery of the CFTR gene in 1989, the search for therapies to improve the basic defects of cystic fibrosis (CF) commenced. Pharmacological manipulation provides the opportunity to enhance CF transmembrane conductance regulator (CFTR) protein synthesis and/or function. CFTR
Bo-Rui Kang et al.
Bioorganic & medicinal chemistry letters, 25(24), 5808-5812 (2015-11-08)
2-Benzylisoquinolin-1(2H)-ones has been proposed as vasodilative agents on the basis of scaffold hopping. In the present study, a series of 2-benzylisoquinolin-1(2H)-ones were synthesized. Their vasodilative effects were evaluated by wire myograph on isolated rat mesenteric arterial ring induced contraction with
Hugo M Botelho et al.
Scientific reports, 5, 9038-9038 (2015-03-13)
Plasma membrane proteins are essential molecules in the cell which mediate interactions with the exterior milieu, thus representing key drug targets for present pharma. Not surprisingly, protein traffic disorders include a large range of diseases sharing the common mechanism of
M Q Zhang et al.
Die Pharmazie, 46(10), 687-700 (1991-10-01)
The rapid growth in the quinolone research changed the whole face of the previous SAR concepts. So far structural modifications at all positions of the quinolone nucleus except the 4-oxo group have successfully lead to the discovery of potent antimicrobial
G L Bundy et al.
The Journal of biological chemistry, 261(2), 747-751 (1986-01-15)
The gorgonian coral Pseudoplexaura porosa contains a lipoxygenase capable of converting exogenous arachidonic acid into (8R)-8-hydroperoxy-5,9,11,14-eicosatetraenoic acid. The (8R)- (or 8-L-) configuration in this product, opposite to that observed in previously reported 8-lipoxygenase products, was determined unambiguously by comparison of

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Discovery C18 and C8 HPLC Columns products offered

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