推荐产品
product name
SUPELCOSIL ™ LC-ABZ HPLC 色谱柱, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
材料
stainless steel column
agency
suitable for USP L60
產品線
SUPELCOSIL™
特點
endcapped
製造商／商標名
SUPELCOSIL™
包裝
1 ea of
標籤範圍
12.0% carbon loading
參數
≤70 °C temp. limit
400 bar pressure (5801 psi)
技術
HPLC: suitable
長度 × 內徑
15 cm × 4.6 mm
表面積
170 m2/g
表面覆盖率
surface coverage 3.4 μmol/m2
基質
silica gel, spherical particle platform
fully porous particle
基質活性組
amide, alkyl phase
粒徑
5 μm
孔徑
120 Å
pH值範圍
2-7.5
應用
food and beverages
分離技術
reversed phase
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一般說明
SUPELCOSIL LC-ABZ 相具有独特的去活技术，该可为碱性化合物以及酸性、中性和非极性化合物提供出色的反相性能。不需要采取使用同类胺在高离子强度下运行，以及调节流动相的极端 pH 值来抑制硅烷醇活性，就可以在 LC-ABZ 相上获得良好的峰形。
應用
- Validation of a high-performance liquid chromatography method for the assay of and determination of related organic impurities in nevirapine drug substance.: This paper validates a method using the SUPELCOSIL™ LC-ABZ HPLC Column for assessing purity and impurities in HIV medication, showcasing the column′s high specificity and reproducibility (Li et al., 2000).
- A comparative study of the reversed-phase HPLC retention behaviour of S-adenosyl-L-methionine and its related metabolites on Hypersil ODS and Supelcosil LC-ABZ stationary phases.: This comparative study provides insights into the retention behaviors of bioactive compounds on SUPELCOSIL™ LC-ABZ, affirming its versatility and robust performance in complex biochemical separations (Valkó et al., 1993).
特點和優勢
• 用于酸性、碱性、两性离子
• 相对于标准反相具有更大的极性保留性
• 独特的选择性
• 硅烷醇去活
• 对于非极性分析物，峰形、柱效和保留性相当于 C8 相
• 相对于标准反相具有更大的极性保留性
• 独特的选择性
• 硅烷醇去活
• 对于非极性分析物，峰形、柱效和保留性相当于 C8 相
法律資訊
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
K Valkó et al.
Journal of pharmaceutical and biomedical analysis, 11(4-5), 361-366 (1993-04-01)
S-Adenosyl-L-methionine (SAM) and its metabolites S-adenosyl-L-homocysteine (SAH) and methyl-thioadenosine (MTA) are endogenous compounds that are heavily involved in a variety of biochemical processes, and have therefore been the target for several assays in body fluids and tissues. Reversed-phase chromatographic behaviour
Q C Li et al.
Journal of chromatographic science, 38(6), 246-254 (2000-07-13)
Nevirapine (Viramune), a dipyridiodiazepinone, is a potent and highly specific nonnucleoside inhibitor of HIV-1 reverse transcriptase. This paper describes the validation of a specific, sensitive, and stability-indicating high-performance liquid chromatography method for the assay and determination of related organic impurities
Murali Pendela et al.
Journal of separation science, 32(20), 3418-3424 (2009-09-19)
Streptomycin (SM) is composed of streptidine, streptose and N-methyl glucosamine sugar moieties. For the determination of SM and its related substances, an ion-pair LC-UV detection method using a Supelcosil LC-ABZ column was developed previously. While analyzing commercial samples, several unknown
D Korakas et al.
Journal of pharmaceutical and biomedical analysis, 12(9), 1141-1145 (1994-09-01)
A series of biologically active peptides and their conjugates with lipidic amino acids were investigated by systematic change of the mobile phase composition using traditional octadecylsilica stationary phase and the newly developed Supelcosil LC-ABZ column. The mobile phases contained various
Ana B Baranda et al.
Journal of chromatography. A, 1031(1-2), 275-280 (2004-04-03)
A high-performance liquid chromatographic method with electrochemical detection was developed for the simultaneous determination of five 1,4-dihydropyridines: amlodipine, nitrendipine, felodipine, lacidipine and lercanidipine. These drugs are widely used in the treatment of hypertension, angina pectoris and the therapy of cerebrovascular
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