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Merck

53338-U

Supelco

Ascentis® Express 90 Å Phenyl-Hexyl (2.7 μm) HPLC Columns

L × I.D. 15 cm × 2.1 mm, HPLC Column

别名:

Core-shell (SPP) Fused Core Phenyl HPLC column

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About This Item

分類程式碼代碼:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Ascentis® Express Phenyl-Hexyl,2.7μm HPLC色谱柱, 2.7 μm particle size, L × I.D. 15 cm × 2.1 mm

材料

stainless steel column

agency

suitable for USP L11

產品線

Ascentis®

特點

endcapped

製造商/商標名

Ascentis®

包裝

1 ea of

參數

60 °C temp. range
600 bar max. pressure (9000 psi)

技術

HPLC: suitable
LC/MS: suitable
UHPLC-MS: suitable
UHPLC: suitable

長度 × 內徑

15 cm × 2.1 mm

表面積

135 m2/g

雜質

<5 ppm metals

基質

Fused-Core particle platform
superficially porous particle

基質活性組

phenylhexyl phase

粒徑

2.7 μm

孔徑

90 Å

pH值範圍

2-9

應用

food and beverages

分離技術

reversed phase

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一般說明

由于溶质与键合相的芳香环及其离域电子发生相互作用,使Phenyl-Hexyl固定相具有独特的选择性。这种独特的芳香基选择性使其与C18和RP-酰胺固定相互补(正交)。Phenyl-Hexyl固定相也倾向于具有良好的形状选择性,这可能来自于溶质与平面环系统的多点相互作用。对于具有芳族吸电子基团(氟、硝基等)或具有离域杂环系统(如苯二氮类化合物)的溶质,通常具有更强的保留性和选择性。

應用

  • A Different Perspective on the Characterization of a New Degradation Product of Flibanserin With HPLC-DAD-ESI-IT-TOF-MSn and Its Pharmaceutical Formulation Analysis With Inter-Laboratory Comparison.: This study utilizes the Ascentis® Express Phenyl-Hexyl, 2.7 μm HPLC column to characterize degradation products of flibanserin, demonstrating its efficacy in high-resolution analytical applications (Geven et al., 2023).
  • HPLC with spectrophotometric or mass spectrometric detection for quantifying very-long chain fatty acids in human plasma and its association with cardiac risk factors.: The AAscentis® Express Phenyl-Hexyl column was employed for precise quantification of fatty acids, linking its use to critical clinical research on cardiac risk factors (Shrestha et al., 2021).
  • A fully automated and fast method using direct sample injection combined with fused-core column on-line SPE-HPLC for determination of ochratoxin A and citrinin in lager beers.: This research highlights the efficiency of the Ascentis® Express Phenyl-Hexyl column in detecting contaminants in beverages, emphasizing its role in food safety analysis (Lhotska et al., 2016).
  • A study of retention characteristics and quality control of nutraceuticals containing resveratrol and polydatin using fused-core column chromatography.: This study explores the retention characteristics of nutraceuticals using the Ascentis® Express Phenyl-Hexyl column, showcasing its utility in quality control of health supplements (Fibigr et al., 2016).
  • An on-line SPE-HPLC method for effective sample preconcentration and determination of fenoxycarb and cis, trans-permethrin in surface waters.: The Ascentis® Express Phenyl-Hexyl column was integral in preconcentrating and analyzing pesticide residues in environmental samples, underscoring its environmental analytical applications (Satinsky et al., 2015).

法律資訊

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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C M Chavez-Eng et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1011, 204-214 (2016-01-17)
An ultra-high performance liquid chromatography/tandem mass spectrometry (UPLC-MS/MS) method for the simultaneous determination of (4S,5R)-5-[3,5-bis (trifluoromethyl)phenyl]-3-{[4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl] methyl}-4-methyl-1,3-oxazolidin-2-one (anacetrapib, I) and [(13)C5(15)N]-anacetrapib, II in human plasma has been developed to support a clinical study to determine the absolute bioavailability of I.
E Lesellier
Journal of chromatography. A, 1266, 34-42 (2012-11-03)
The recent introduction of new stationary phases for liquid chromatography based on superficially porous particles, called core-shell or fused-core, dramatically improved the separation performances through very high efficiency, due mainly to reduced eddy diffusion. However, few studies have evaluated the
Petr Chocholouš et al.
Talanta, 103, 221-227 (2012-12-04)
Currently, for Sequential Injection Chromatography (SIC), only reversed phase C18 columns have been used for chromatographic separations. This article presents the first use of three different stationary phases: three core-shell particle-packed reversed phase columns in flow systems. The aim of
Ivona Lhotská et al.
Analytical and bioanalytical chemistry, 408(12), 3319-3329 (2016-03-20)
A new fast and sensitive method based on on-line solid-phase extraction on a fused-core precolumn coupled to liquid chromatography with fluorescence detection has been developed for ochratoxin A (OTA) and citrinin (CIT) determination in lager beer samples. Direct injection of
Alex D Batista et al.
Talanta, 133, 142-149 (2014-12-02)
On-line sample pretreatment (clean-up and analyte preconcentration) is for the first time coupled to sequential injection chromatography. The approach combines anion-exchange solid-phase extraction and the highly effective pentafluorophenylpropyl (F5) fused-core particle column for separation of eight sulfonamide antibiotics with similar

商品

Improve your reversed phase selectivity for polar aromatics and heterocyclic compounds with the Ascentis® Express Phenyl-Hexyl U/HPLC column.

Improve your reversed phase selectivity for polar aromatics and heterocyclic compounds with the Ascentis® Express Phenyl-Hexyl U/HPLC column.

Chromatograms

application for HPLC

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