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Key Documents

WH0255631M7

Sigma-Aldrich

Monoclonal Anti-COL24A1 antibody produced in mouse

clone 1D8, purified immunoglobulin, buffered aqueous solution

别名:

Anti-collagen, type XXIV, alpha 1

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

1D8, monoclonal

形狀

buffered aqueous solution

物種活性

human

技術

indirect ELISA: suitable
western blot: 1-5 μg/mL

同型

IgG2aκ

GenBank登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

一般說明

Collagen type XXIV α 1 (COL24A1) is part of the fibril-forming family of collagen molecules and is expressed in bones.

免疫原

COL24A1 (NP_690850, 1626 a.a. ~ 1714 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
PRWTSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSWHKATFLFHTQEPNQLPVIEVQKLPHLKTERKYYIDSSSVCFL

生化/生理作用

Collagen type XXIV α 1 (COL24A1) takes part in modulating various processes in the cartilage and bone. It has been linked to head and neck squamous cell carcinoma.

外觀

Solution in phosphate buffered saline, pH 7.4

法律資訊

GenBank is a registered trademark of United States Department of Health and Human Services

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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CREB-AP1 protein complexes regulate transcription of the collagen XXIV gene (Col24a1) in osteoblasts.
Matsuo N
The Journal of Biological Chemistry, 281(9), 5445-5452 (2006)
Kiyoshi Misawa et al.
Molecular and clinical oncology, 2(2), 285-291 (2014-03-22)
Squamous cell carcinoma of the head and neck (HNSCC) is the sixth most common type of cancer, affecting ~500,000 individuals worldwide annually. Collagen is the major constituent of the extracellular matrix component in tumors and plays a crucial role in

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