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UC448

硫酸对乙酰氨基酚钾盐钾盐

Name: 硫酸对乙酰氨基酚钾盐 钾盐
Brand: SIGMA

solid, ≥97% (HPLC)

别名:

4-乙酰氨基苯酚硫酸酯钾盐, N-（4-亚砜基苯基）乙酰胺单钾盐, 硫酸对乙酰氨基酚钾盐

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About This Item

经验公式（希尔记法）:

C₈H₈KNO₅S

CAS号:

32113-41-0

分子量:

269.32

MDL號碼:

MFCD01631667

分類程式碼代碼:

12161501

PubChem物質ID:

329827671

NACRES:

NA.77

化驗

≥97% (HPLC)

形狀

solid

顏色

white to off-white

mp

163 °C

溶解度

H₂O: soluble

儲存溫度

2-8°C

SMILES 字串

[K+].CC(=O)Nc1ccc(OS([O-])(=O)=O)cc1

InChI

1S/C8H9NO5S.K/c1-6(10)9-7-2-4-8(5-3-7)14-15(11,12)13;/h2-5H,1H3,(H,9,10)(H,11,12,13);/q;+1/p-1

InChI 密鑰

AJYPYWFCUWHZMZ-UHFFFAOYSA-M

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一般說明

对乙酰氨基酚是一种氨基酚衍生物。具有镇痛解热作用，致炎作用弱。对乙酰氨基酚用于治疗发热和轻度至中度疼痛。它可能通过抗氧化作用抑制动脉粥样硬化。

應用

硫酸对乙酰氨基酚钾盐已用作对乙酰氨基酚 HPLC 含量测定的标准品。

生化／生理作用

对乙酰氨基酚的 II 相代谢产物。

包裝

无底玻璃瓶。内含物装在插入的融合锥内。

準備報告

硫酸对乙酰氨基酚钾盐溶于水。

其他說明

偶尔，可能需要以钠盐形式供应

象形圖

GHS05,GHS07

訊號詞

Danger

危險聲明

H315,H317,H318,H335

防範說明

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

危險分類

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

分析证书(COA)

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Slide 1 of 4

1 of 4

Supelco

A-064

醋氨酚溶液

Y0001781

设备鉴定用扑热息痛

Sigma-Aldrich

A4438

p-Acetamidophenyl β-D-glucuronide sodium salt

Sigma-Aldrich

SML1777

Propacetamol hydrochloride

Paracetamol: past, present, and future.

Prescott LF

American Journal of Therapeutics, 7(2), 143-147 (2000)

Intra- and interindividual variability of glucuronidation of paracetamol during repeated administration of propacetamol in neonates.

Karel Allegaert et al.

Acta paediatrica (Oslo, Norway : 1992), 94(9), 1273-1279 (2005-11-11)

Major changes in drug clearance and metabolism are observed during infancy, in part based on ontogenic regulation of various metabolic pathways. Since paracetamol provides a good substrate to study UGT (1A6) activity, urinary metabolites of propacetamol were determined in neonates

Immune thrombocytopenia resulting from sensitivity to metabolites of naproxen and acetaminophen.

D Bougie et al.

Blood, 97(12), 3846-3850 (2001-06-05)

In patients suspected of having drug-induced immune thrombocytopenia, antibodies reactive with normal platelets in the presence of the suspect drug can sometimes be identified, but negative results are often obtained. One reason for this is that drug metabolites, formed in

Sulphation deficit in "low-functioning" autistic children: a pilot study.

A Alberti et al.

Biological psychiatry, 46(3), 420-424 (1999-08-06)

Parents of autistic children and autism support groups often report that autistic episodes are exacerbated when the children eat certain foodstuffs such as dairy products, chocolates, wheat, corn sugar, apples, and bananas. The hypothesis that autistic behavior might be related

Altered hepatobiliary disposition of acetaminophen glucuronide in isolated perfused livers from multidrug resistance-associated protein 2-deficient TR(-) rats.

H Xiong et al.

The Journal of pharmacology and experimental therapeutics, 295(2), 512-518 (2000-10-25)

Previous studies have demonstrated that phenobarbital treatment impairs the biliary excretion of acetaminophen glucuronide (AG), although the transport system(s) responsible for AG excretion into bile has not been identified. Initial studies in rat canalicular liver plasma membrane vesicles indicated that

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