推荐产品
生物源
human
重組細胞
expressed in CHO cells
籤條
FLAG® tagged
化驗
>95% (SDS-PAGE)
形狀
lyophilized
分子量
35-40 kDa by SDS-PAGE
包裝
pkg of 10 μg
儲存條件
avoid repeated freeze/thaw cycles
雜質
<0.01 EU/μg endotoxin, tested
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... CD40LG(959)
一般說明
CD40L (cluster of differentiation 40 ligand) belongs to the tumor necrosis factor (TNF) family, and is expressed by basophils, B cells, monocytic cells, natural killer cells, platelets, mast cells and T cells. It is predominantly expressed on pro-inflammatory T cells. It also exists in a soluble form.
生化／生理作用
CD40L (cluster of differentiation 40 ligand) is active in its membrane-bound form. It interacts with CD40 and functions as a proinflammatory and procoagulant agent. The serum levels of soluble CD40L is elevated in malignant middle cerebral artery infarction (MMCAI) patients, especially in non-surviving patients.
外觀
Lyophilized from PBS
重構
Reconstitute with 100 μL deionized water.
其他說明
Human CD40L (aa 116-261) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag.
法律資訊
FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Association between Serum Soluble CD154 Levels and Mortality in Patients with Malignant Middle Cerebral Artery Infarction.
Lorente L, et al.
International Journal of Molecular Sciences, 16(6), 12147-12158 (2015)
Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex.
Holler N, et al.
Molecular and Cellular Biology, 23(4), 1428-1440 (2003)
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