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Merck
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Key Documents

SRP6506

Sigma-Aldrich

Haptoglobin Plasma (MixedType) from human plasma

≥95% (SDS-PAGE)

别名:

Bp, Haptoglobin b-Chain, Hp, haptoglobin a-chain

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

human plasma

化驗

≥95% (SDS-PAGE)

形狀

lyophilized

分子量

monomer 200 kDa (Hp 2-1)
monomer 400 kDa (Hp 2-2)
monomer 86 kDa (Hp 1-1)

包裝

pkg of 1 mg

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

human ... HP(3240)

一般說明

An acute-phase plasma protein found in human plasma at 100-300 mg/100 mL. Binds hemoglobin, thus preventing loss of iron through the kidneys. Humans are polymorphic for haptoglobin, with three major phenotypes: Hp 1-1, Hp 2-1, and Hp 2-2. While the phenotypic distribution can vary greatly between ethnicities and geographic location, the Hp 2-1 phenotype is the most prevalent phenotype in humans. Plasma concentrations of haptoglobin are highest in individuals with Hp 1-1, intermediate in Hp 2-1 individuals, and lowest in Hp 2-2 individuals. Hp 1-1 is the most effective at binding hemoglobin, and Hp 2-2 is the least effective. This functional difference may be associated with the frequency and severity of epilepsy attacks, as researchers have found a correlation between recurring seizures and the Hp 2-2 phenotype.

外觀

Lyophilized as a salt-free solid.

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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