推荐产品
相关类别
一般說明
β-NGF 是与 BDNF、NT-3 和 NT-4 结构相关的神经营养因子。这些蛋白质属于生长因子的半胱氨酸结家族，其具有稳定的二聚体结构。β-NGF 是一种强神经营养因子，通过其受体 β-NGFR 传递信号，在感觉和交感神经系统的发育和保存中起着至关重要的作用。β-NGF 还作为 B 淋巴细胞的生长和分化因子，并促进 B 细胞的存活。人 β-NGF 的功能形式是非共价二硫键连接的同源二聚体，具有两个 13.5kDa 多肽单体（总共 240 个氨基酸残基）。这三个二硫键是生物活性所必需的。
應用
人β NGF 已被用于免疫组织化学。
生化／生理作用
β-NGF 是与 BDNF、NT-3 和 NT-4 结构相关的神经营养因子。人 b-NGF 的功能形式是非共价二硫键连接的同源二聚体，具有两个 13.5kDa 多肽单体（总共 240 个氨基酸残基）。这三个二硫键是生物活性所必需的。
序列
SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRRA
外觀
冻干品，无添加剂。
重構
在打开之前离心小瓶。在水中重悬至浓度为 0.1-1.0 mg/ml。不要涡旋。该溶液可在 2-8℃ 下储存长达 1 周。要于长期储存，建议在含有载体蛋白（例如 0.1％ BSA）的缓冲液中进一步稀释，并以 工作等分试样储存于 -20°C 至 -80°C。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
H Zhang et al.
European journal of histochemistry : EJH, 59(3), 2522-2522 (2015-10-03)
The nerve growth factor (NGF) not only has an essential effect on the nervous system, but also plays an important role in a variety of non-neuronal systems, such as the reproductive system. The aim of this study was to investigate
The nerve growth factor 35 years later.
R Levi-Montalcini
Science (New York, N.Y.), 237(4819), 1154-1162 (1987-09-04)
A Ullrich et al.
Nature, 303(5920), 821-825 (1983-06-30)
Nerve growth factor (NGF) is thought to have a profound effect on the development and maintenance of sympathetic and embryonic sensory neurones (see refs 1-3 for review). NGF activity isolated from the male mouse submaxillary gland (MSG) consists of three
Li Xiao et al.
Neural regeneration research, 15(12), 2270-2272 (2020-07-01)
As an aging-associated degenerative disease, Alzheimer's disease is characterized by the deposition of amyloid beta (Aβ), oxidative stress, inflammation, dysfunction and loss of cholinergic neurons. Colla Corii Asini (CCA) is a traditional Chinese medicine which has been used for feebleness-related
Benita Wiatrak et al.
Cells, 9(4) (2020-04-17)
The PC12 cell line is one of the most commonly used in neuroscience research, including studies on neurotoxicity, neuroprotection, neurosecretion, neuroinflammation, and synaptogenesis. Two types of this line are available in the ATCC collection: traditional PC12 cells grown in suspension
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门