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Merck
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主要文件

SRP2025

Sigma-Aldrich

p52 human

recombinant, expressed in E. coli, ≥70% (SDS-PAGE)

别名:

DFS70, LEDGF, MGC74712, PAIP, p52

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About This Item

分類程式碼代碼:
12352202
NACRES:
NA.26

生物源

human

重組細胞

expressed in E. coli

化驗

≥70% (SDS-PAGE)

形狀

frozen liquid

分子量

~39 kDa

包裝

pkg of 10 μg

濃度

600 μg/mL

顏色

clear colorless

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... PSIP1(11168)

生化/生理作用

The human p52 protein is a non-TAF transcription coactivator that mediates activator-dependent transcription by RNA polymerase II. The function of p52 is through interactions with transcriptional activators and the basal transcription machinery. In addition, p52 may also interact with several cellular proteins including the transcription coactivator PC4, the essential splicing factor ASF/SF2 and the nuclear protein nucleolin.

外觀

Clear and colorless frozen liquid solution

準備報告

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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H Ge
Nucleic acids research, 28(2), e3-e3 (1999-12-22)
Protein-protein interactions have been widely used to study gene expression pathways and may be considered as a new approach to drug discovery. Here I report the development of a universal protein array (UPA) system that provides a sensitive, quantitative, multi-purpose
H Ge et al.
Molecular cell, 2(6), 751-759 (1999-01-14)
Increasing evidence suggests that pre-mRNA splicing can take place cotranscriptionally in vivo. However, insight into how these two processes are linked has been lacking. Here, we describe that a novel transcriptional coactivator, p52, interacts not only with transcriptional activators and
H Ge et al.
The EMBO journal, 17(22), 6723-6729 (1998-11-21)
Transcriptional activation in human cell-free systems containing RNA polymerase II and general initiation factors requires the action of one or more additional coactivators. Here, we report the isolation of cDNAs encoding two novel human transcriptional coactivators (p52 and p75) that

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