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Key Documents

SRP0465

Sigma-Aldrich

BRDT (257-382) His tag human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

别名:

BRD6, CT9, bromodomain, testis-specific

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About This Item

分類程式碼代碼:
12352200
NACRES:
NA.32

生物源

human

重組細胞

expressed in E. coli

化驗

≥90% (SDS-PAGE)

形狀

aqueous solution

分子量

15.8 kDa

包裝

pkg of 100 μg

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... BRDT(676)

一般說明

Human Bromodomain testis-specific protein, also known as BRDT, BRD6, and CT9 (GenBank Accession No. NM_207189) amino-acids 257 – 382 with N-terminal HIS-tag, MW = 15.8 kDa, expressed in an E. coli expression system.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Enyuan Shang et al.
Development (Cambridge, England), 134(19), 3507-3515 (2007-08-31)
Brdt is a testis-specific member of the distinctive BET sub-family of bromodomain motif-containing proteins, a motif that binds acetylated lysines and is implicated in chromatin remodeling. Its expression is restricted to the germ line, specifically to pachytene and diplotene spermatocytes
Binyamin D Berkovits et al.
Developmental biology, 360(2), 358-368 (2011-10-25)
Mice homozygous for a mutation (Brdt(∆BD1/∆BD1)) lacking the first bromodomain of Brdt, a testis-specific member of the BET family of double-bromodomain containing proteins, are sterile and exhibit profound defects in chromatin remodeling during spermiogenesis. We have now observed that a

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