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Merck
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Key Documents

SRP0462

Sigma-Aldrich

BRD4 (342-460) His tag human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

别名:

CAP, HUNK1, HUNKI, MCAP, bromodomain containing 4

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About This Item

分類程式碼代碼:
12352200
NACRES:
NA.32

生物源

human

重組細胞

expressed in E. coli

化驗

≥90% (SDS-PAGE)

形狀

aqueous solution

分子量

14.7 kDa

包裝

pkg of 100 μg

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... BRD4(23476)

一般說明

Human Bromodomain containing 4, also known as BRD4, HUNK1, or MCAP (GenBank Accession No. NM_058243) amino-acids 342-460 with N-terminal His-tag, MW = 14.7 kDa, expressed in an E. coli expression system.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Philipp Voigt et al.
Genome biology, 12(11), 133-133 (2011-12-01)
The chromatin adapter BRD4 may be crucial for transmitting epigenetic information by acting as a histone acetylation-dependent gene bookmark and accelerating post-mitotic transcriptional reactivation.
R M Rodriguez et al.
Journal of molecular medicine (Berlin, Germany), 90(5), 587-595 (2011-11-29)
The bromodomain protein BRD4 is involved in cell proliferation and cell cycle progression, primarily through its role in acetylated chromatin-dependent regulation of transcription at targeted loci. Here, we show that BRD4 is frequently downregulated by aberrant promoter hypermethylation in human

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