推荐产品
生物源
mouse
重組細胞
expressed in baculovirus infected Sf9 cells
形狀
aqueous solution
分子量
62 kDa
包裝
pkg of 10 μg
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−70°C
基因資訊
mouse ... EGFR(13649)
一般說明
Mouse EGFR (GenBank Accession No. NM_207655/ NP_997538), amino acids 670-1210 with C-terminal Flag-tag, MW = 62 kDa, expressed in SF9 cells via a Baculovirus expression system.
應用
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Ariel Talavera et al.
Molecular immunology, 48(12-13), 1578-1585 (2011-05-20)
The EGF receptor is an important target of cancer immunotherapies. The 7A7 monoclonal antibody has been raised against the murine EGFR, but it cross-reacts with the human receptor. The results from experiments using immune-competent mice can therefore, in principle, be
Jeffrey D Kearns et al.
Molecular cancer therapeutics, 14(7), 1625-1636 (2015-04-26)
Although EGFR is a validated therapeutic target across multiple cancer indications, the often modest clinical responses to current anti-EGFR agents suggest the need for improved therapeutics. Here, we demonstrate that signal amplification driven by high-affinity EGFR ligands limits the capacity
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