SML3970

S1RA

≥98% (HPLC)

• 别名: 4-{2-[5-Methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy]ethyl}morpholine, E 52862, E-52862, E52862, MR 309, MR-309, MR309
• 经验公式（希尔记法）: C₂₀H₂₃N₃O₂
• CAS号: 878141-96-9
• 分子量: 337.42
• MDL號碼: MFCD25976945
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: , White to light Brown
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: room temp

说明

生化／生理作用

Selective, high-affinity sigma-1 receptor antagonist with antinociceptive efficacy in vivo.



S1RA (E-52862) is a selective, high-affinity sigma-1 receptor antagonist (human/guinea pig σ1 Ki = 17/23.5 nM; σ2 Ki = 9.3 μM/rat, >1 μM/guinea pig). S1RA exerts dose-dependent antinociceptive effects in several neuropathic pain models in mice in vivo (16 - 64 mg/kg i.p.).

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable