SML3782

Omadacycline tosylate

≥97% (HPLC)

• 别名: MK-2764 tosylate, (4S,4aS,5aR,12aS)-4,7-bis(Dimethylamino)-9-(2,2-dimethylpropylaminomethyl)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12aoctahydrotetracene-2-carboxamide, 4-methylbenzenesulfonate, Amadacycline tosylate, BAY 73-7388 tosylate, MK 2764 tosylate, MK2764 tosylate, PTK 0796 tosylate, PTK-0796 tosylate, PTK0796 tosylate
• 经验公式（希尔记法）: C₂₉H₄₀N₄O₇·C₇H₈O₃S
• CAS号: 1075240-43-5
• 分子量: 728.85
• MDL號碼: MFCD28167752
• 分類程式碼代碼: 51111800
• 分類程式碼代碼: 12352200
• NACRES: NA.21

属性

• 品質等級: 100
• 化驗: ≥97% (HPLC)
• 形狀: powder
• 儲存條件: desiccated
• 顏色: yellow to orange
• 溶解度: H₂O: 2 mg/mL, clear
• 儲存溫度: -10 to -25°C

说明

生化／生理作用

Omadacycline (amadacycline, PTK 0796) is an orally active, potent tetracycline-class antibacterial against broad gram-positive and some gram-negative bacteria, including strains expressing the two main forms of tetracycline resistance (efflux and ribosomal protection). Omadacycline is also active against Haemophilus influenzae (H. influenzae) and atypical and anaerobic pathogens, including Legionella pneumophila, Mycoplasma spp., Ureaplasma spp., Bacteroides spp., and Clostridioides difficile. Unlike tetracycline, Omadacycline is active in vitro in the presence of the ribosomal protection protein Tet(O), despite its ribosomal binding site is similar to that of tetracycline.

注意

Hygroscopic

安全信息

• 象形圖: GHS08
• 訊號詞: Warning
• 危險聲明: H361d,H362
• 防範說明: P202 - P260 - P263 - P264 - P280 - P308 + P313
• 危險分類: Lact. - Repr. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable