SML3779

Methotrexate disodium salt

≥98% (HPLC)

• 别名: Amethopterin sodium, N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid disodium salt, Sodium methotrexate
• 经验公式（希尔记法）: C₂₀H₂₀N₈Na₂O₅
• CAS号: 7413-34-5
• 分子量: 498.40
• MDL號碼: MFCD00274560
• 分類程式碼代碼: 12352200
• NACRES: NA.21

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 儲存條件: desiccated
• 顏色: white to brown
• 溶解度: H₂O: 2 mg/mL, clear
• 儲存溫度: -10 to -25°C
• SMILES 字串: [Na].[Na].N([C@@H](CCC(=O)O)C(=O)O)C(=O)c1ccc(cc1)N(Cc2nc3c(nc(nc3N)N)nc2)C
• InChI 密鑰: HQRCOVOSZPGUCA-GXKRWWSZSA-N

说明

生化／生理作用

Folic acid antagonist that is used as an antineoplastic and antirheumatic drug

Methotrexate disodium salt is a potent is a folic acid antagonist that is used as an antineoplastic and antirheumatic drug. Methotrexate disodium salt is a potent inhibitor of dihydrofolate reductase.

注意

Hygroscopic

安全信息

• 象形圖: GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H301,H315,H319,H341,H360D
• 防範說明: P202 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• 危險分類: Acute Tox. 3 Oral - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable