SML3439

IXA4

98% (HPLC)

• 别名: N-​Methyl-​N-​[2-​(4-​methylphenoxy)​ethyl]​-​4-​[(1-​oxo-​3-​phenoxypropyl)​amino]​-1H-​pyrazole-​1-​acetamide
• 经验公式（希尔记法）: C₂₄H₂₈N₄O₄
• CAS号: 1185329-96-7
• 分子量: 436.50
• MDL號碼: MFCD13023943
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: 98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: −20°C
• SMILES 字串: O=C(CN1N=CC(NC(CCOC2=CC=CC=C2)=O)=C1)N(C)CCOC3=CC=C(C=C3)C
• InChI: 1S/C24H28N4O4/c1-19-8-10-22(11-9-19)32-15-13-27(2)24(30)18-28-17-20(16-25-28)26-23(29)12-14-31-21-6-4-3-5-7-21/h3-11,16-17H,12-15,18H2,1-2H3,(H,26,29)
• InChI 密鑰: ZVSKMVAWWBSNOY-UHFFFAOYSA-N

说明

生化／生理作用

IXA4 is a nontoxic, potent and highly selective IRE1-XBP1s signaling activator that induce ER proteostasis remodeling. IXA4 reduced Aβ levels and prevents APP-associated mitochondrial dysfunction in CHO7PA2 cells expressing the V717F APP (APPV717F) mutant.

Nontoxic, potent and highly selective IRE1-XBP1s signaling activator that induce ER proteostasis remodeling

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable