SML3366

SIS17

≥95% (HPLC)

• 别名: N′-Hexadecylthiophene-2-carbohydrazide, SIS 17, SIS-17
• 经验公式（希尔记法）: C₂₁H₃₈N₂OS
• CAS号: 2374313-54-7
• 分子量: 366.60
• MDL號碼: MFCD32201127
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear (Warmed)
• 儲存溫度: -10 to -25°C

说明

生化／生理作用

SIS17 is a potent and selective HDAC11 inhibitor (IC50 = 830 nM; IC50 >100 μM against HDAC1/4/8 or SIRT1/2/3/6) that effectively upregulates HDAC11 substrate, serine hydroxymethyl transferase 2 (SHMT2), fatty acylation level in MCF7 cells (12.5 μM).

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable