SML3277
HDL mimetic peptide 4F trifluoroacetate
≥95% (HPLC)
别名:
Ac-DWFKAFYDKVAEKFKEAF-NH2 trifluoroacetate, L-4F trifluoroacetate, N-Acetyl-L-α-aspartyl-L-tryptophyl-L-phenylalanyl-L-lysyl-L-alanyl-L-phenylalanyl-L-tyrosyl-L-α-aspartyl-L-lysyl-L-valyl-L-alanyl-L-α-glutamyl-L-lysyl-L-phenylalanyl-L-lysyl-L-α-glutamyl-L-alanyl-L-phenylalaninamide trifluoroacetate
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About This Item
分類程式碼代碼:
12352200
NACRES:
NA.77
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生化／生理作用
HDL mimetic peptide 4F is a brain blood barrier penetrant small amphipathic peptide that exhibits anti-inflammatory, antioxidant and anti-atherogenic properties in animal models. HDL mimetic peptide 4F increases the brain efflux of intracerebrally injected 125I-Aβ42. It suppresses proinflammatory monocytes and macrophages and alleviates post myocardial infarction remodeling in a mouse model.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Barbara Pavan et al.
Drug discovery today, 22(7), 1123-1130 (2017-05-24)
Several olfactory receptors (ORs) have been characterized outside the olfactory neuroepithelium in neuronal and non-neuronal tissues, where they were implicated in the recognition of diverse chemical signals. ORs have been found to regulate melanogenesis in skin melanocytes, and OR expression
Daniela Busse et al.
The Journal of investigative dermatology, 134(11), 2823-2832 (2014-07-08)
As the outermost barrier of the body, the skin is exposed to multiple environmental factors, including temperature, humidity, mechanical stress, and chemical stimuli such as odorants that are often used in cosmetic articles. Keratinocytes, the major cell type of the
Jérémy Chéret et al.
Nature communications, 9(1), 3624-3624 (2018-09-20)
Olfactory receptors are expressed by different cell types throughout the body and regulate physiological cell functions beyond olfaction. In particular, the olfactory receptor OR2AT4 has been shown to stimulate keratinocyte proliferation in the skin. Here, we show that the epithelium
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