SML3031

塞来昔布

≥98% (HPLC), powder, cyclooxygenase-2 inhibitor

• 别名: 4- [5-（4-甲基苯基）-3-（三氟甲基）-1H-吡唑-1-基] 苯磺酰胺, CJ-016377, CP-598107, PF-00345549, PHA-00846533, SC-58635, YM-177
• 经验公式（希尔记法）: C₁₇H₁₄F₃N₃O₂S
• CAS号: 169590-42-5
• 分子量: 381.37
• MDL號碼: MFCD00941298
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• product name: 塞来昔布, ≥98% (HPLC)
• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• SMILES 字串: Cc1ccc(cc1)-c2cc(nn2-c3ccc(cc3)S(N)(=O)=O)C(F)(F)F
• InChI: 1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
• InChI 密鑰: RZEKVGVHFLEQIL-UHFFFAOYSA-N

说明

生化／生理作用

塞来昔布是一种非甾体类抗炎药 (NSAID) 和环氧化酶-2 (COX-2) 选择性抑制剂。塞来昔布对 COX-2 的选择性至少是 COX-1 的 10-20 倍。

Celecoxib is a non-steroidal, anti-inflammatory drug (NSAID) and a cyclooxygenase-2 (COX-2) selective inhibitor. Celecoxib is at least 10-20 times more selective for COX-2 over COX-1.

安全信息

• 象形圖: GHS08,GHS09
• 訊號詞: Danger
• 危險聲明: H360D,H373,H410
• 防範說明: P202 - P260 - P273 - P280 - P308 + P313 - P391
• 危險分類: Aquatic Chronic 1 - Repr. 1B - STOT RE 2
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable