SML2980

G6PDi-1

≥98% (HPLC)

• 别名: 4-([5-oxo-6H,7H,8H,9H-cyclohepta[d]pyrimidin-2-yl]amino)thiophene-2-carbonitrile
• 经验公式（希尔记法）: C₁₄H₁₂N₄OS
• CAS号: 2457232-14-1
• 分子量: 284.34
• MDL號碼: MFCD32899271
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: N#CC1=CC(NC2=NC=C3C(CCCCC3=N2)=O)=CS1
• InChI: 1S/C14H12N4OS/c15-6-10-5-9(8-20-10)17-14-16-7-11-12(18-14)3-1-2-4-13(11)19/h5,7-8H,1-4H2,(H,16,17,18)
• InChI 密鑰: USWCHVCZOGGQQA-UHFFFAOYSA-N

说明

生化／生理作用

G6PDi-1 is a cell penetrant potent and selective nonsteroidal inhibitor of glucose-6-phosphate dehydrogenase (G6PD). G6PDi-1 strongly depletes NADPH in lymphocytes. It decreases inflammatory cytokine response in macrophages, and suppresses respiratory burst in neutrophils.

cell penetrant potent and selective nonsteroidal inhibitor of glucose-6-phosphate dehydrogenase (G6PD)

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable