SML2975
Dabcyl-KTSAVLQSGFRKME-Edans trifluoroacetate
≥95% (HPLC), powder, FRET substrate of SARS-CoV Mpro
别名:
DABCYL-Lys-Thr-Ser-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg-Lys-Met-Glu-EDANS trifluoroacetate, N2-[4-[[4-(Dimethylamino)phenyl]azo]benzoyl]-L-lysyl-L-threonyl-L-seryl-L-alanyl-L-valyl-L-leucyl-L-glutaminyl-L-serylglycyl-L-phenylalanyl-L-arginyl-L-lysyl-L-methionyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-L-α-glutamine trifluoroacetate
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About This Item
经验公式（希尔记法）:
C95H141N25O24S2 · xC2HF3O2
CAS号:
分子量:
2081.42 (free base basis)
分類程式碼代碼:
12352200
NACRES:
NA.77
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product name
Dabcyl-KTSAVLQSGFRKME-Edans trifluoroacetate, ≥95% (HPLC)
品質等級
化驗
≥95% (HPLC)
形狀
powder
顏色
light brown to dark red
儲存溫度
−20°C
生化／生理作用
Dabcyl-KTSAVLQSGFRKME-Edans is a fluorescence resonance energy transfer (FRET) substrate for SARS-CoV main protease Mpro (also called 3CLpro) (538 nm with excitation at 355 nm). Dabcyl-KTSAVLQSGFRKME-Edans is suitable to measure protease activity of COVID-19 virus Mpro, SARS-CoV Mpro, and other viruses.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Linlin Zhang et al.
Journal of medicinal chemistry, 63(9), 4562-4578 (2020-02-12)
The main protease of coronaviruses and the 3C protease of enteroviruses share a similar active-site architecture and a unique requirement for glutamine in the P1 position of the substrate. Because of their unique specificity and essential role in viral polyprotein
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