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Merck
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主要文件

SML2973

Sigma-Aldrich

MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 trifluoroacetate

≥95% (HPLC)

别名:

N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-alanyl-L-valyl-L-leucyl-L-glutaminyl-L-serylglycyl-L-phenylalanyl-L-arginyl-N6-(2,4-dinitrophenyl)-L-lysyl-L-Lysinamide trifluoroacetate

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About This Item

经验公式（希尔记法）:
C69H99N19O20 · xC2HF3O2
CAS号:
932391-88-3
分子量:
1514.64 (free base basis)
分類程式碼代碼:
12352200
NACRES:
NA.77

品質等級

100

化驗

≥95% (HPLC)

形狀

film or powder

顏色

white to yellow

儲存溫度

−20°C

生化／生理作用

FRET substrate suitable to measure protease activity of COVID-19 virus Mpro, SARS-CoV Mpro, and some other viruses
MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 is a fluorescence resonance energy transfer (FRET) substrate derived from the N-terminal auto-cleavage fragment of the SARS-CoV Mpro viral protease ((excitation wavelengths 320 nm and emission wavelengths 405 nm). MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 is suitable to measure protease activity of COVID-19 virus Mpro, SARS-CoV Mpro, and other viruses.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Xiaoyu Xue et al.
Journal of molecular biology, 366(3), 965-975 (2006-12-27)
The viral proteases have proven to be the most selective and useful for removing the fusion tags in fusion protein expression systems. As a key enzyme in the viral life-cycle, the main protease (M(pro)) is most attractive for drug design

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