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SML2644

Sigma-Aldrich

NCGC00135472

≥98% (HPLC)

别名:

3,4-Difluoro-N-[3-(3-methylimidazo[1,2-a]pyrimidin-2-yl)phenyl]-benzamide, C2A

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About This Item

经验公式（希尔记法）:
C20H14F2N4O
CAS号:
862811-76-5
分子量:
364.35
分類程式碼代碼:
12352200
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

powder

顏色

white to beige

溶解度

DMSO: 2 mg/mL, clear

儲存溫度

room temp

SMILES 字串

Fc1c(ccc(c1)C(=O)Nc2cc(ccc2)c3nc4[n](c3C)cccn4)F

InChI

1S/C20H14F2N4O/c1-12-18(25-20-23-8-3-9-26(12)20)13-4-2-5-15(10-13)24-19(27)14-6-7-16(21)17(22)11-14/h2-11H,1H3,(H,24,27)

InChI 密鑰

YOVZCQZBMAXLPR-UHFFFAOYSA-N

生化／生理作用

NCGC00135472 (C2A) is a resolvin D1 (RvD1) mimetic that activates resolving D1 receptor (DRV1/GPR32) and stimulate phagocytosis of serum-treated zymosan. NCGC00135472 enhances macrophage phagocytosis of live E. coli.
resolvin D1 (RvD1) mimetic that activates DRV1/GPR32

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Nan Chiang et al.
Cell chemical biology, 26(2), 244-254 (2018-12-18)
Resolution of acute inflammation is governed, in part, by specialized pro-resolving mediators, including lipoxins, resolvins, protectins, and maresins. Among them, resolvin D1 (RvD1) exhibits potent pro-resolving functions via activating human resolvin D1 receptor (DRV1/GPR32). RvD1 is a complex molecule that requires

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