SML2616

Bepotastine besilate

≥98% (HPLC)

• 别名: (+)-4-[[(S)-p-chloro-alpha-2­pyridylbenzyl]oxy]-1-piperidine butyric acid monobenzenesulfonate, Bepreve
• 经验公式（希尔记法）: C₂₁H₂₅ClN₂O₃ · C₆H₆O₃S
• CAS号: 190786-44-8
• 分子量: 547.06
• MDL號碼: MFCD01938491
• 分類程式碼代碼: 51111800
• NACRES: NA.77

属性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 光學活性: [α]/D 4.5 to 6.5°, c = 1 in methanol
• 儲存條件: desiccated
• 顏色: white to beige
• 儲存溫度: −20°C
• SMILES 字串: [S](=O)(=O)(O)c4ccccc4.Clc1ccc(cc1)[C@@H](OC3CCN(CC3)CCCC(=O)O)c2ncccc2
• InChI: 1S/C21H25ClN2O3.C6H6O3S/c22-17-8-6-16(7-9-17)21(19-4-1-2-12-23-19)27-18-10-14-24(15-11-18)13-3-5-20(25)26;7-10(8,9)6-4-2-1-3-5-6/h1-2,4,6-9,12,18,21H,3,5,10-11,13-15H2,(H,25,26);1-5H,(H,7,8,9)/t21-;/m1./s1
• InChI 密鑰: UDGHXQPQKQPSBB-ZMBIFBSDSA-N

说明

生化／生理作用

Bepotastine besilate is a second generation antihistamine used clinically for the treatment of itching associated with allergic conjunctivitis, allergic rhinitis and urticaria/pruritus. It is a direct H1-receptor antagonist that inhibits the release of histamine from mast cells.

Second generation antihistamine, H1-receptor antagonist

安全信息

• 象形圖: GHS08
• 訊號詞: Warning
• 危險聲明: H361d
• 防範說明: P201 - P202 - P280 - P308 + P313 - P405 - P501
• 危險分類: Repr. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable