SML2532

Jedi2

≥98% (HPLC)

• 别名: 2-Methyl-5-(2-thienyl)-3-furancarboxylic acid
• 经验公式（希尔记法）: C₁₀H₈O₃S
• CAS号: 651005-90-2
• 分子量: 208.23
• MDL號碼: MFCD01569561
• 分類程式碼代碼: 12352200

属性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear
• 儲存溫度: 2-8°C
• InChI: 1S/C10H8O3S/c1-6-7(10(11)12)5-8(13-6)9-3-2-4-14-9/h2-5H,1H3,(H,11,12)
• InChI 密鑰: YXDCRSXNEOKXDE-UHFFFAOYSA-N

说明

生化／生理作用

Jedi2 is an activator of the mechanosensitive Piezo1 channel that binds at a different place from Yoda1. It exhibits long-range allosteric gating, activating Piezo1 through the extracellular side of its peripheral blade-like structure rather than the C-terminal extracellular domain of the pore.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302 - H315 - H317 - H319
• 防範說明: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable