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Merck

SML2169

Sigma-Aldrich

地芬尼多 盐酸盐

≥98% (HPLC)

别名:

1,1-二苯基-4-(1-哌啶基)-1-丁醇, 戴芬逸多

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About This Item

经验公式(希尔记法):
C21H27NO · HCl
CAS号:
分子量:
345.91
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

powder

儲存條件

desiccated

顏色

white to beige

溶解度

H2O: 2 mg/mL, clear (warmed)

儲存溫度

2-8°C

SMILES 字串

Cl.OC(CCCN1CCCCC1)(c2ccccc2)c3ccccc3

InChI

1S/C21H27NO.ClH/c23-21(19-11-4-1-5-12-19,20-13-6-2-7-14-20)15-10-18-22-16-8-3-9-17-22;/h1-2,4-7,11-14,23H,3,8-10,15-18H2;1H

InChI 密鑰

AVZIYZHXZAYGJS-UHFFFAOYSA-N

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生化/生理作用

Diphenidol is a non-selective muscarinic acetylcholine receptor antagonist. Diphenidol is an antiemetic agent used in the treatment of vomiting and vertigo.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Lin Zhang et al.
Forensic science, medicine, and pathology, 11(4), 570-576 (2015-10-21)
Diphenidol hydrochloride (DPN), a nonphenothiazinic antiemetic agent used primarily in patients with Meniere disease and labyrinthopathies to treat vomiting and vertigo, is considered to be a relatively safe drug. Since it was first approved in the United States in 1967
Yu-Wen Chen et al.
Neuroscience letters, 552, 62-65 (2013-08-07)
Diphenidol has been shown to block voltage-gated Na(+) channels, which are associated with specific types of pain. Here, we evaluated the effects of diphenidol on chronic constriction injury (CCI)-evoked allodynia and expression of tumor necrosis factor-α (TNF-α). A peripheral nerve

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