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Merck

SML2036

Sigma-Aldrich

Gigantol

≥98% (HPLC)

别名:

5-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-2-methoxyphenol, CID 3085362

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About This Item

经验公式(希尔记法):
C16H18O4
CAS号:
分子量:
274.31
MDL號碼:
分類程式碼代碼:
12352200
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

oil

顏色

colorless to light brown

儲存溫度

2-8°C

InChI

1S/C16H18O4/c1-19-14-8-12(7-13(17)10-14)4-3-11-5-6-16(20-2)15(18)9-11/h5-10,17-18H,3-4H2,1-2H3

InChI 密鑰

SDXKZPQOVUDXIY-UHFFFAOYSA-N

生化/生理作用

Gigantol is a bibenzyl compound isolated from Dendrobium orchids (Dendrobium aphyllum, Dendrobium draconis, Dendrobium aurantiacum, etc.) that exhibits potent cytotoxic activity against several cancer cell lines. It inhibits the migratory behavior of non-small cell lung cancer cells. Gigantol inhibits galactose-induced formation of cataracts through repression of the gene expression and activity of AR and iNOS.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Pornprom Klongkumnuankarn et al.
Evidence-based complementary and alternative medicine : eCAM, 2015, 350410-350410 (2015-02-17)
Chromatographic separation of a methanol extract prepared from the whole plant of Dendrobium brymerianum led to the isolation of eight phenolic compounds. Among the isolated compounds (1-8), moscatilin (1), gigantol (3), lusianthridin (4), and dendroflorin (6) showed appreciable cytotoxicity against
Huanhuan Chen et al.
Oncology reports, 37(2), 865-870 (2016-12-14)
Gigantol is a phenolic substance extracted from plants in the genus Dendrobium and used in traditional Chinese medicine. In the present study, we aimed to investigate the growth inhibition and apoptotic effects of gigantol on human liver cancer cells through
Sopanya Charoenrungruang et al.
Journal of natural products, 77(6), 1359-1366 (2014-05-23)
Lung cancer is one of the most common causes of cancer death due to its high metastasis potential. The process of cancer migration is an early step that is required for successful metastasis. The discovery and development of natural compounds

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