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化驗
≥98% (HPLC)
形狀
oil
顏色
colorless to light brown
儲存溫度
2-8°C
InChI
1S/C16H18O4/c1-19-14-8-12(7-13(17)10-14)4-3-11-5-6-16(20-2)15(18)9-11/h5-10,17-18H,3-4H2,1-2H3
InChI 密鑰
SDXKZPQOVUDXIY-UHFFFAOYSA-N
生化/生理作用
Gigantol is a bibenzyl compound isolated from Dendrobium orchids (Dendrobium aphyllum, Dendrobium draconis, Dendrobium aurantiacum, etc.) that exhibits potent cytotoxic activity against several cancer cell lines. It inhibits the migratory behavior of non-small cell lung cancer cells. Gigantol inhibits galactose-induced formation of cataracts through repression of the gene expression and activity of AR and iNOS.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Evidence-based complementary and alternative medicine : eCAM, 2015, 350410-350410 (2015-02-17)
Chromatographic separation of a methanol extract prepared from the whole plant of Dendrobium brymerianum led to the isolation of eight phenolic compounds. Among the isolated compounds (1-8), moscatilin (1), gigantol (3), lusianthridin (4), and dendroflorin (6) showed appreciable cytotoxicity against
Oncology reports, 37(2), 865-870 (2016-12-14)
Gigantol is a phenolic substance extracted from plants in the genus Dendrobium and used in traditional Chinese medicine. In the present study, we aimed to investigate the growth inhibition and apoptotic effects of gigantol on human liver cancer cells through
Journal of natural products, 77(6), 1359-1366 (2014-05-23)
Lung cancer is one of the most common causes of cancer death due to its high metastasis potential. The process of cancer migration is an early step that is required for successful metastasis. The discovery and development of natural compounds
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