SML1595

Luliconazole

≥98% (HPLC)

• 别名: (αE)-α-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-1H-imidazole-1-acetonitrile, NND 502, [R-(E)]-α-[4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-1H-imidazole-1-acetonitrile
• 经验公式（希尔记法）: C₁₄H₉Cl₂N₃S₂
• CAS号: 187164-19-8
• 分子量: 354.28
• MDL號碼: MFCD00953915
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329825485
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 20 mg/mL, clear
• 儲存溫度: −20°C
• SMILES 字串: N#C/C(N1C=NC=C1)=C2SC[C@@H](C3=C(Cl)C=C(Cl)C=C3)S/2
• InChI: 1S/C14H9Cl2N3S2/c15-9-1-2-10(11(16)5-9)13-7-20-14(21-13)12(6-17)19-4-3-18-8-19/h1-5,8,13H,7H2/b14-12+/t13-/m0/s1
• InChI 密鑰: YTAOBBFIOAEMLL-REQDGWNSSA-N

说明

一般說明

Luliconazole also called LLCZ, {(−)-(E)-[(4R)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene](1H-imidazol-1-yl) acetonitrile} is optically active compound. It is used as a topical medicine for treating dermatophytosis and dermatitis. It is a potential antifungal against Candida and other fungal infections of skin, groin and feet.

生化／生理作用

Luliconazole is an imidazole antifungal. Its mechanism of action involves inhibition of ergosterol biosynthesis by inhibition of sterol 14α-demethylase.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319
• 防範說明: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable