SML1284

Efavirenz Ready Made Solution

10 mg/mL in DMSO

• 别名: (4S)-6-Chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one, (4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
• 经验公式（希尔记法）: C₁₄H₉ClF₃NO₂
• CAS号: 154598-52-4
• 分子量: 315.67
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 形狀: DMSO solution
• 品質等級: 200
• 濃度: 10 mg/mL in DMSO
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• InChI: 1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1
• InChI 密鑰: XPOQHMRABVBWPR-ZDUSSCGKSA-N

说明

生化／生理作用

Efavirenz is a nonnucleoside reverse transcriptase inhibitor (NNRTI). Efavirenz is an anti-HIV drug, commonly used in combination therapy for AIDs treatment. Efavirenz is part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1.

The plasma levels of this drug can determine the failure of treatment and CNS (central nervous system) side-effects in patients infected with HIV (human immunodeficiency virus).

安全信息

• 象形圖: GHS08,GHS09
• 訊號詞: Danger
• 危險聲明: H360,H411
• 防範說明: P202 - P273 - P280 - P308 + P313 - P391 - P405
• 危險分類: Aquatic Chronic 2 - Repr. 1B
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 188.6 °F
• 閃點（°C）: 87 °C