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化驗
≥95% (HPLC)
形狀
powder
顏色
white to off-white
運輸包裝
wet ice
儲存溫度
−20°C
Amino Acid Sequence
H-Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH trifluoroacetate salt
生化/生理作用
铁调素-25 是铁调素的主要同种型。铁调素-25 中的网织红细胞血红蛋白含量 (CHr) 有助于鉴别 DA 可将缺铁性贫血 (IDA) 与慢性病贫血 (ACD) 及 ACD/IDA 合并状态相鉴别。铁调素基因突变与严重青少年血色病的发生有关。
铁调素是铁稳态的主要调节因子。铁调素存在于肝脏中,但也广泛分布于脑中,可能在预防铁相关的神经退行性病变中发挥作用。铁调素具有抗炎和抗菌活性。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Association of prohepcidin and hepcidin-25 with erythropoietin response and ferritin in hemodialysis patients.
American Journal of Nephrology, 28(1), 115-121 (2008)
Journal of analytical methods in chemistry, 2018, 9653747-9653747 (2018-07-18)
As advanced mass spectrometry- (MS-) based hepcidin analysis offers to overcome the limitations in analytical methods using antihepcidin, further improvement of MS detection sensitivity for the peptide may enhance the diagnostic value of the hepcidin for various iron-related disorders. Here
Serum hepcidin?25 may replace the ferritin index in the Thomas plot in assessing iron status in anemic patients.
International Journal of Laboratory Hematology, 33(2), 187-193 (2011)
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis.
Nature Genetics, 33(1), 21-21 (2003)
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